for sale bulk 3598-...

for sale bulk 3598-37-6 Acepromazine Maleate In China
for sale bulk 3598-37-6 Acepromazine Maleate In China
for sale bulk 3598-37-6 Acepromazine Maleate In China
for sale bulk 3598-37-6 Acepromazine Maleate In China
for sale bulk 3598-37-6 Acepromazine Maleate In China

for sale bulk 3598-37-6 Acepromazine Maleate In China

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99% min
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

3598-37-6 Acepromazine Maleate In China CAS 3598-37-6 bulk CAS 3598-37-6 Acepromazine Maleate for sale

Quick Details

  • Appearance:White Powder
  • Application:Animal Pharmaceuticals
  • PackAge:> 1kg: Packed with aluminium bags with ziplock bags inside. > 25kg: Packed with paper drum with double plastic bags inside.
  • ProductionCapacity:10000|Kilogram|Day
  • Storage:Stay in cool&dry place
  • Transportation:CNF/CPT/CIF/FOB

Superiority:

Acepromazine is a phenothiazine antipsychotic, analog of chlorpromazine , and a dopamine receptor antagonist. It also binds to muscarinic receptors in rat brain (IC50 = 350 nM) and inhibits contractions of guinea pig ileum induced by acetylcholine . Acepromazine inhibits morphine-induced vomiting in dogs. It also inhibits development of a conditioned avoidance response, unconditioned escape response, and catalepsy in rats (ED50s = 0.98, 3.1, and 17 mg/kg, respectively). Formulations containing acepromazine have been used as tranquilizers and anesthetics premedicant in small and large animal veterinary care.

Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine (#C8138). The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.

Details:

 Acepromazine maleate, also known as Sch-10649, is a dopamine D1/2 receptor and 5-HT1A/2A receptor antagonist used to prevent nausea and induce sedation.

Catalogue Number A130900
Chemical Name Acepromazine Maleate
Synonyms 1-[10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone (2Z)-2-Butenedioate; 10-[3-(Dimethylamino)propyl]phenothiazin-2-yl Methyl Ketone Maleate; Acepran; Acepromazine Monomaleate; Acetylpromazine Maleate; Anatran; Atravet; Calmivet; Calmo Neosan; NSC 264522; Notensil; Notenzil; Plegicil; Sedalin; Soprontin;
CAS Number 3598-37-6
Molecular Formula C??H??N?OS • C ?H?O?
Appearance Light Yellow to Yellow Solid
Melting Point 135-138°C
Molecular Weight 326.46 + (116.07)
Storage -20°C Freezer
Solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications A tranquilizer.

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