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3598-37-6 Acepromazine Maleate price CAS 3598-37-6 top quality CAS 3598-37-6 High Purity
A derivative of Acepromazine. Acepromazine is a phenothiazine derivative antipsychotic drug. It was used on humans during the 1950s as an antipsychotic, but is now almost exclusively used on animals as a sedative and antiemetic
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine. Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Acepromazine is commonly used as a veterinary drug (horses, dogs and cats).
Acepromazine maleate, dopamine, 5-HT1 and 5-HT2 receptor antagonist
Non-selective dopamine, 5-HT1 and 5-HT2 receptor antagonist. Antipsychotic agent.
Non-selective dopamine, 5-HT1 and 5-HT2 receptor antagonist. Antipsychotic agent. Phenothiazine derivative. Shows strong antiadrenergic and weaker peripheral anticholinergic activity. Shows anxiolytic and sedative effects in vivo. Orally active.
3598-37-6
Acepromazine is intended for Pharmaceuticals applications. All information about Acepromazine maleate salt is provided in the MSDS. We deliver compounds with high purity levels and a comprehensive Certificate of Analysis. Connect to your member account to consult the documents.
Acepromazine is a phenothiazine antipsychotic, analog of chlorpromazine (Cay-16129), and a dopamine receptor antagonist. It also binds to muscarinic receptors in rat brain (IC50 = 350 nM) and inhibits contractions of guinea pig ileum induced by acetylcholine (Cay-23829, IC50 = 840 nM). Acepromazine inhibits morphine-induced vomiting in dogs. It also inhibits development of a conditioned avoidance response, unconditioned escape response, and catalepsy in rats (ED50s = 0.98, 3.1, and 17 mg/kg, respectively). Formulations containing acepromazine have been used as tranquilizers and anesthetics premedicant in small and large animal veterinary care. Formal Name: 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]-ethanone, mono-2Z-butenedioate. CAS Number: 3598-37-6. Synonyms: ACE, Acetylpromazine, NSC 264522. Molecular Formula: C19H22N2OS . C4H4O4. Formula Weight: 442.5. Purity: >98%. Formulation: A solid. Solubility: DMF: 1mg/mL, DMSO: 3mg/mL, Ethanol: 2mg/mL, PBS (pH 7.2): 2mg/mL. lambdamax: 242, 278 nm. SMILES: CN(C)CCCN1C2=C(C=CC(C(C)=O)=C2)SC3=CC=CC=C31.OC(/C=C\C(O)=O)=O. InChi Code: InChI=1S/C19H22N2OS.C4H4O4/c1-14(22)15-9-10-19-17(13-15)21(12-6-11-20(2)3)16-7-4-5-8-18(16)23-19,5-3(6)1-2-4(7)8/h4-5,7-10,13H,6,11-12H2,1-3H3,1-2H,(H,5,6)(H,7,8)/b,2-1-. InChi Key: FQRHOOHLUYHMGG-BTJKTKAUSA-N.
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