Supply CAS 38183-03-8 DHF 7 8-Dihydroxyflavone Powder

Supply CAS 38183-03-8 DHF 7 8-Dihydroxyflavone Powder

Min.Order / FOB Price:Get Latest Price

10 Gram	FOB Price:USD 10.0000 -100.0000

10 Gram

FOB Price:USD 10.0000 -100.0000

Min.Order :10 Gram
Purity: 99%
Payment Terms : L/C|D/A|D/P|T/T|||Other

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Quick Details

Appearance:White Powder
Application:Health Proctect, Health Proctect
PackAge:25G~1KG/FOIL BAG
ProductionCapacity:||
Storage:Cool Dry Place
Transportation:By DHL/ By Fedex/ By EMS/By TNT/By Sea /By Air

Details:

Products Description

Supply CAS38183-03-8 DHF 7 8-Dihydroxyflavone Powder
Product Name	7,8-DIHYDROXYFLAVONE
CAS No	38183-03-8
MF	C15H10O4
MW	254.24
Melting Point	243-246°C
Boiling Point	494.4±45.0 °C(Predicted)
Density	1.443±0.06 g/cm3(Predicted)
Storage	Store at +4°C
Solubility	DMSO: soluble24mg/mL

Introduction:

7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). 7,8-DHF is both orally bioavailable and able to penetrate the blood–brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease.

Real Shot

Application & Function:

7,8-DHF has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome.

7,8-DHF also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents.

In addition, 7,8-DHF possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.

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1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

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Company Profile

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development

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1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

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