CAS 103639-04-9 Ondansetron Hydrochloride Ondansetron Hcl

CAS 103639-04-9 Ondansetron Hydrochloride Ondansetron Hcl

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10 Gram	FOB Price:USD 10.0000 -15.0000

10 Gram

FOB Price:USD 10.0000 -15.0000

Min.Order :10 Gram
Purity: 99%
Payment Terms : L/C|D/A|D/P|T/T|||Other

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Quick Details

Appearance:White Powder
Application:Medicine Grade, Medicine Grade
PackAge:25G~1KG/FOIL BAG
ProductionCapacity:||
Storage:Cool Dry Place
Transportation:By DHL/ By Fedex/ By EMS/By TNT/By Sea /By Air

Details:

Products Description

CAS 103639-04-9 Ondansetron Hydrochloride Ondansetron Hcl
Name	Ondansetron
Synonyms	1,2,3,4-Tetrahydro-9-methyl-3-(2-methyl-1H-imidazol-1-ylmethyl)carbazol-4-one
Molecular Formula	C18H19N3O
Molecular Weight	293.37
CAS Registry Number	99614-02-5 (116002-70-1)

Real Shot

Application & Function:

Ondansetron hydrochloride is an antiemetic ondansetron hydrochloride. Its pharmacological effects is similar with ondansetron, and ondansetron hydrochloride is a potent, highly selective 5-HT3 receptor antagonist, which has a strong antiemetic effect of chemotherapy, radiotherapy and post-operative nausea effect, that is better than metoclopramide.

Ondansetron, granisetron, and dolasetron are three common clinical antiemetic. Ondansetron is an effective, reversible and selective serotonin (5-HT3) blocker. It have little effect for α1, α2, β1, β2-adrenergic receptor and the histamine H1, H2 receptor, which have minimal effect on H receptors, central and peripheral dopaminergic receptor antagonistic effect. It can be suppressed by the chemotherapy and radiotherapy-induced nausea and vomiting. Compared with metoclopramide, it has strong antiemetic effect without extrapyramidal reactions. . can produce rapid and strong antiemetic effect. Suitable for the treatment of nausea and vomiting, nausea, vomited by the cytotoxic chemotherapy and radiation therapy. It can also prevent and treat nausea and vomit induced by surgically .

Specification

Test items	Standard	Test results
Description	White or almost white crystalline powder	white crystalline powder
Solubilit	Slightly soluble in water ,very slightly soluble in methanol, practically insoluble in ethano	Complies
Identificatio	IR vs standard	Complies
Identificatio		Test for specific optical rotation	Complies
Appearance of solution	The solution is clear and colorless	Complies
Acidity	Not more than 0.6ml of 0.01M Naoh is required to change the color of the indicator to pink	0.44ml
Specific optical rotatio	+74.5°~+78.0°	+75.6°
Related substances	ImpurityA:NMT0.1%	0.03%
		Impurity B: NMT0.1%	0.05%
		Impurity C: NMT0.1%	0.03%
		Any other impurity:NMT0.1%	0.05%
		Total of other impurities:NMT0.1%	0.06%
		Total of impurities:NMT0.3%	0.16%
Impurity D	NMT0.1%	0.01%
Loss on drying	NMT0.5%	0.19%
Assay	98~102% (dried substance)	99.85%
Bacterial endotoxins	<1.0IU/mg	Complies

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.

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