Supply 99% Setipiprant Anti Hair Loss Setipiprant

Supply 99% Setipiprant Anti Hair Loss Setipiprant

Min.Order / FOB Price:Get Latest Price

10 Gram	FOB Price:USD 6.5000 -8.5000

10 Gram

FOB Price:USD 6.5000 -8.5000

Min.Order :10 Gram
Purity: 99%
Payment Terms : L/C|D/A|D/P|T/T||MoneyGram|Other

Keywords

Quick Details

Appearance:White Powder
Application:Anti Hair Loss, Anti Hair Loss
PackAge:25G~1KG/FOIL BAG
ProductionCapacity:||
Storage:Cool Dry Place
Transportation:By DHL/ By Fedex/ By EMS/By TNT/By Sea /By Air

Details:

Products Description

Supply 99% Setipiprant Anti Hair Loss Setipiprant
Product Name:	Setipiprant
Aaasy:	99%
CAS:	866460-33-5
Appearance:	White fine powder
Testing Method:	HPLC
Function:	Anti-hair loss

Introduction:

Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.

Real Shot

Application & Function:

1.For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase.

2.Which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.

3.Setipiprant powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.Setipiprant needs to be applied once or twice daily for hair to be maintained

Applicaiton/Dosage

Scalp hair loss Acting through DP2, PGD2 can inhibit hair growth, suggesting that this receptor is a potential target for bald treatment. A phase 2A study to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo in 18 to 49 year old males with androgenetic.Setipiprant proved to be well-tolerated and reasonably effective in reducing allergen-induced airway responses in asthmatic patient clinical trials.

Specification

Items	Requirements	Results
Appearance:	White powder	White powder
Identification	A. IR B. HPLC	Conforms
Loss on drying	≤0.5%	0.19%
Identification A	IR spectrum corresponds to the reference chloramphenicol standard	Conforms
Related Substance	Individual impurity ≤0.5% Total impurity ≤1.5%	0.06% 0.09%
Heavy metal Pb : Cadmium(Cd) : As : Hg:	≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm	<10ppm Conforms 0.3ppm Conforms Negative

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SM04554	1360540-81-3
ODM-201	1297538-32-9

Our Review:

FAQ

1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery；
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian

Company Profile

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development

Why Choose Us

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

Package & Delivery