Supply API Melatonin Agonist Powder Ramelteon Powder For Insomnia

Supply API Melatonin Agonist Powder Ramelteon Powder For Insomnia

Min.Order / FOB Price:Get Latest Price

1 Gram	FOB Price:USD 20.0000 -49.0000

1 Gram

FOB Price:USD 20.0000 -49.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C|D/A|D/P|T/T|||Other

Keywords

Quick Details

Appearance:White Powder
Application:Pharmaceutical Intermediates, Pharmaceutical Intermediates
PackAge:25G~1KG/FOIL BAG
ProductionCapacity:||
Storage:Cool Dry Place
Transportation:By DHL/ By Fedex/ By EMS/By TNT/By Sea /By Air

Details:

Products Description

Supply 99% CAS 196597-26-9 Ramelteon Powder
Product Name	Ramelteon
Synonyms	Rozerem (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethyl]propionamide
CAS	196597-26-9
Molecular Formula	C16H21NO2
Molecular Weight	259.34
Density	1.119g/cm3
Melting Point	113-115°C
Boiling Point	455.3°C at 760 mmHg
Flash Point	229.2°C
Refractive Index	1.555
Vapour Pressure	1.77E-08mmHg at 25°C
Storage	Room temperature
Appearance	White powder

Introduction:

Ramelteon is a sleep agent that selectively binds to the MT1 and MT2 receptors in the suprachiasmatic nucleus (SCN), instead of binding to GABAA receptors.

It however does not appear to speed the onset of sleep or the amount of sleep a person gets. It is approved by the U.S. Food and Drug Administration for long-term use.

Ramelteon does not show any appreciable binding to GABAA receptors, which are associated with anxiolytic, myorelaxant, and amnesic effects.

Real Shot

Ramelteon is the first selective melatonin agonist. It works by mimicking melatonin (MT), a naturally occuring hormone that is produced during the sleep period and thought to be responsible for the regulation of circadian rhythm underlying the normal sleep-wake cycle. Ramelteon has a high affinity for the MT1 and MT2 receptors. The MT1 and MT2 receptors are located in the brain's suprachiasmatic nuclei (SCN),which is known as the body's "master clock" because it regulates the 24-hour sleep-wake cycle. Ramelteon has an active metabolite that is less potent but circulates in higher concentrations than the parent compound.

The metabolite also has weak affinity for the 5HT2b receptor.

Specification

ITEM	SPECIFICATION
Physical Appearance	White to off-white, free-flow powders
Purity (gamma-PGA)	99% (by HPLC)
Molecular Weight	700 KDA (by GPC/HPLC)
Loss on Drying	5% max., by automatic infrared analyzer
PH	5.0~7.0
Clarity, OD400(4% aq. sol’n)	0.07 max
Heavy metals	Total as Pb: 10 ppm max.
TPC (CFU/g)	500 max.
E.coli	Negative
Salmonella	Negative
Particle size	100% thru 100 mesh

Our Review:

FAQ

1. who are we?
We are based in Shaanxi, China, start from 2018,sell to North America(00.00%),Western Europe(00.00%),South America(00.00%),Southeast Asia(00.00%),Eastern Europe(00.00%). There are total about 11-50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Plant Extracts,Cosmetics Raw Materials,Vitamin Raw Materials,Pharmaceutical Raw Materials and Intermediates

4. why should you buy from us not from other suppliers?
Our company mainly devoted in producing pharmacetical intermediates , Vitamins , and health supplement , the quality and technical content can reach the advance level in China .Our products are sold well in China as well as in more than 20 countries

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,Express Delivery；
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,MoneyGram,Credit Card,,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,Arabic,French,Russian,Korean,Hindi,Italian

Company Profile

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development

Why Choose Us

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

Package & Delivery