Supply Tamoxifen Citrate CAS 10540-29-1 Tamoxifen / Nolvadex Powder

Details:

Supply Tamoxifen Citrate CAS 10540-29-1 Tamoxifen Nolvadex Powder

Alias:	tamoxifen free base; genox; kessar; nolvadex; nolvadex-d; tamoxen; (z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethylethanamine; 2-{4-[(1z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-n,n-dimethylethanamin
CAS	10540-29-1
MF:	C26H29No
MW:	371.65
Properties:	White Crystal Powder
Melting Point:	95～98℃
Content:	≥99%
Packing:	10～1000g aluminium foil bag; 5～25kg fiber can or according to customer requirements
Standards:	EP
Storage:	10～20t/year
Yield:	in cool and ventilated warehouse under the temperature lower than 30℃; the storage period is 3 years。

Tamoxifen (tmx), sold under the brand name nolvadex among others, is a medication that is used to prevent breast 

cancer in women and treat breast cancer in women and men. it is also being studied for other types of cancer.it has

been used for albright syndrome. tamoxifen is typically taken daily by mouth for five years for breast cancer.

 

Serious Side effects include a small increased risk of uterine cancer, stroke, vision problems, and pulmonary embolism.

common side effects include irregular periods, weight loss, and hot flashes. it may cause harm to the baby if taken

during pregnancy or breastfeeding. it is a selective estrogen-receptor modulator (serm) that works both by decreasing

factors that increase the growth of breast cells and increasing factors that decrease the growth of breast cells. it is of

the triphenylethylene group.

 

Tamoxifen was discovered in 1967. it is on the world health organization's list of essential medicines, the most effective

and safe medicines needed in a health system.tamoxifen is available as a generic medication.

Medical Use:

Breast Cancer:

Tamoxifen is currently used for the treatment of both early and advanced estrogen receptor (er)-positive (er+) breast

cancer in pre- and post-menopausal women. additionally, it is the most common hormone treatment for male breast

cancer. it is also approved by the fda for the prevention of breast cancer in women at high risk of developing the

disease. it has been further approved for the reduction of contralateral (in the opposite breast) cancer. the use of

tamoxifen is recommended for 10 years.

 

in 2006, the large star clinical study concluded that raloxifene is equally effective in reducing the incidence of breast

cancer, but after an average 4-year follow-up there were 36% fewer uterine cancers and 29% fewer blood clots in

women taking raloxifene than in women taking tamoxifen, although the difference was not statistically significant.

infertility

Tamoxifen is used to treat infertility in women with anovulatory disorders. it is given at days 3–7 of a woman's cycle.

tamoxifen improves fertility in males with infertility by disinhibiting the hypothalamic-pituitary-adrenal axis

(via er antagonism) and thereby increasing the secretion of luteinizing hormone and follicle-stimulating hormone

and increasing testicular test osterone production.

 

Gynecomastia:

Tamoxifen is used to prevent estrogen-related gynecomastia, resulting from elevated estrogenic levels. it is taken as

a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity.

other drugs are taken for similar purposes such as clomiphene citrate and the anti-aromatase drugs which are used

in order to try to avoid the hormone-related adverse effects. tamoxifen is also sometimes used to treat or prevent

gynecomastia in sex offenders undergoing temporary chemical castration.

 

Others:

Occasionally tamoxifen is used in treatment of the rare conditions of retroperitoneal fibrosis and idiopathic sclerosing

mesenteritis.

 

 

1. Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen

receptor modulator used to prevent breast cancer in women and treat breast cancer in women

and men. It is also being studied for other types of cancer.

 

2. Tamoxifen is used for the treatment of both early and advanced estrogen receptor-positive

breast cancer in pre-and post-menopausal women. Additionally, it is the most common hormone

treatment for male breast cancer . It is also approved by the FDA for the prevention of breast

cancer in women at high risk of developing the disease. It has been further approved for the

reduction of contralateral cancer. The use of tamoxifen is recommended for 10 years.

 

3. Tamoxifen has been used effectively to improve blood flow, reduce uterine contractility and

pain in dysmenorrhea patients.

 

4. Tamoxifen is used for ovulation induction to treat infertility in women with anovulatory

disorders It is giben at days three to seven of a woman's cycle.

 

5. Tamoxifen is used to prevent and treat gynecomastia. It is taken as a preventative measure

in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity.

Other medications are taken for similar purposes such as clomifene and the anti-aromatase

drugs which are used in order to try to avoid the hormone-related adverse effects.

 

Item	Specification	Results
Appearance Identification Residue on ignition Heavy metals Water Specific optical rotation Impurity Spirooxiran 1 Spirooxiran 2 Exemestane related(compound c) Exemestane related(compound a) Any unspecified impurity Total impurity Assay(hplc) Micron	white crystalline powder ir rt (hplc) 0.1% max 10ppm max 0.5% max +290° to +300° 0.15% max 0.15% max 0.15% max 0.15% max 0.1% max 0.5% max 98% to 10.2% 100% less than 20μm	Conform Conform Conform 0.04% Conform 0.03% +290.86° Not Detected Not Detected Not Detected Not Detected 0.05% 0.25% 100.02% Conform
Conclusion: up to standard for usp pending monograph

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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