Factory Supply Veterinary Powder CAS 70288-86-7 Bulk Ivermectin

Details:

Production Name	Ivermectin
CAS	70288-86-7
EINECS	274-536-0
Appearance	White Powder
MF	C95H146O28
MW	1736.16
Melting Point	154.5~157ºC
Usage	Animal Pharmaceuticals
Storage	Keep in a cool, dry, dark location
Shelf Life	24 months when properly stored

Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.

    

Function 

1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus.
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract.
5. Ivermectin has selective inhibition.
6. Ivermectin can not go through the blood brain barrier of humanbeings.

 

Application 

In veterinary medicine ivermectin is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.
It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin.
Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats is available.
Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.

Specification

Product Name	Ivermectin
Appearance	White or yellowish-white crystalline powder
Solubility	Practically insoluble in water, freely soluble immethylene chloride,soluble in alcohol.
Identification	A:Melting range 168-172ºC
IR	Corresponds with that of CRS standard
HPLC	The retention time for H2B1a and H2B1b corresponds with that of standard preparation
Appearance of solution	Clear and not more intensely colored than BY1
Specific optical rotation(anhydrous and solvent-free substance)	-17 ~ -20
Related substances	Individual impurity(RRT1.3-1.5)≤2.5
	Any other individual impurity≤1
	Total ≤5
	Disregard limit≤0.05
Ethanol and Formamide(%)	Ethanol≤5.0
	Formamide≤3.0
Heavy metal(%)	≤0.002
Water(%)	≤1.0
Sulphated ash(%)	≤0.1
Residue of solvent(toluene)	≤890ppm
Assay(%)(HPLC,on dry basis)	H2B1a(H2B1a+H2B1b)≥90.0
	95.0≤H2B1a+H2B1b≤102.0

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q1.What's your MOQ
Our MOQ is 10pcs.
Q2: How to contact with us
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.
Q4:Can you give me a discount price
A: Sure,it depends on your quantity.
Q5:How can I get a sample
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.
Q6: How to confirm the Product Quality before placing orders
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.
Q7:How can I make payment safe
A: The whole transaction is under Alibaba's (Third party) inspection.
Q8: Is it possible to custom the labels with our own design
A: Yes, just send us your artworks, you will get what you want.

Q9.Can I get the sample
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).
Q10.Can you accept customized
Yes,we can according your require to do it.
Q11.How do I place the order
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.