Sarms Powder CAS 1379686-30-2 GW501516 Powder GSK-516 For Bodybuilding

Details:

What's GW501516

gw501516 usage:

it had been investigated as a potential treatment for obesity, diabetes, dyslipidemia and cardiovascular disease.

gw501516 could be used by athletes as an ergogenic performance enhancing drug.

how gw501516 works

endurobol is a selective agonist (activator) of the pparδ receptor. it displays high affinity (ki = 1 nm) and potency

(ec50 = 1 nm) for pparδ with > 1000 fold selectivity over pparα and pparγ.

it activates amp-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and gw 501516 has

been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most

likely by stimulating fatty acid oxidation. it has been proposed as a potential treatment for obesity and related

conditions, especially when used in conjunction with a synergistic compound aicar, as the combination has been

shown to significantly increase exercise endurance in human.

Function & Application：

1. gw-501516, better known as cardarine, is a unique medication officially classified as a ppar receptor agonist (ppar-ra).

research for this medication began in 1992 in a conjoined effort between glaxosmithkline (gsk) and ligand

pharmaceuticals.

 

2. research into this product was set forth in an effort to provide treatment for various cardiovascular diseases,

as well as diabetes, obesity and other conditions.

 

3. it was soon discovered that the ppar-ra was highly effective at enhancing endurance, but it was also shown to

carry a high potential cost. it was discovered that cardarine increased the chances of cancer significantly,

and as a result, gsk dropped all further research.

 

4. however, the studies that produced cancerous results used doses of cardarine that were 500 to even 1000 times

the amount that a human being would take. if cancer is a risk with standard dosing is unknown.

 

5. cardarine (gw-501516) binds to the ppar receptor, specifically a group of nuclear receptors (sensors that detect

thyroid and steroidal hormones in the body) that initiates the pgc-1a enzyme.

 

6. this action leads to gene expression, specifically genes that revolve around energy expenditure. studies involving

gw-501516 have shown to increase the metabolism of fatty acids in rats.

 

7. it was also shown in the same studies to reduce the odds of obesity despite poor eating habits as well as prevent

type-2 diabetes.

 

8. cardarine was also shown to increase hdl (good cholesterol) and decrease ldl (bad cholesterol) in a study using

monkeys. the effects seemed to hold true with or without exercise

 

 

 

 

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4. OEM/ODM Available.

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6. Sample is available for your evaluation & Formulation development.

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2) 30 Days Warranty of quality of goods. 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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