Manufacturer Supply 99% Raw Powder CAS 330784-47-9 Avanafil in Stock with Best Price

Details:

Product Name: Avanafil
Synonyms: 4-[[(3-Chloro-4-Methoxyphenyl)Methyl] aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;Avanafil PDE5 inhibitor;vanafil;(S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;Avanafil 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;avanfil;(S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-yl
CAS: 330784-47-9
MF: C23H26ClN7O3
MW: 483.95
Melting point: 150-152°C
Density: 1.372
Storage temp.: Refrigerator
Appearance: White powder

Description:

Avanafil (Zepeed) was approved by the Korean Health Ministry for the treatment of erectile dysfunction (ED) in August 2011. Avanafil is a highly selective type 5 phosphodiesterase (PDE5) inhibitor. Avanafil is reported to be the most selective PDE5 inhibitor on the market. The onset of Tmax and half-life also varies among the marketed PDE5 inhibitors. Sildenafil has a Tmax at 1 h and a half-life of 3-5 h. Vardenafil is somewhat similar with a Tmax of 0.6 h and a half-life of 4-6 h. Tadalafil has the longest half-life among the marketed drugs with a half-life of 17 h. Avanafil has a fast onset of action reaching Tmax in 0.6 h with a half-life of 1.2 h. A synthesis of avanafil (TA-1790) is described in the patent literature. The main elimination route of avanafil is through the bile and feces. Avanafil was also found to be reabsorbed through enterohepatic recirculation. 

    

Function

avanafil used as vasodilator, Ca channel blocker; Zanarnivir influenza prophylaxis and therapy;
dihydropyridine calcium channel blocker.

Uses:
A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.

Specification

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q1.What's your MOQ
Our MOQ is 10pcs.
Q2: How to contact with us
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.
Q4:Can you give me a discount price
A: Sure,it depends on your quantity.
Q5:How can I get a sample
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.
Q6: How to confirm the Product Quality before placing orders
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.
Q7:How can I make payment safe
A: The whole transaction is under Alibaba's (Third party) inspection.
Q8: Is it possible to custom the labels with our own design
A: Yes, just send us your artworks, you will get what you want.

Q9.Can I get the sample
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).
Q10.Can you accept customized
Yes,we can according your require to do it.
Q11.How do I place the order
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.