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10 Gram |
Negotiable |
Methylprednisolone 83-43-2 CAS NO.83-43-2
English name: Methylprednisolone
Molecular Formula:C22H30O5
Molecular Weight:374.4706
CAS Registry Number:83-43-2
EINECS:201-476-4
Quality:BP/CP
Density:1.28g/cm3
Melting point:228-237°C (dec.)
Boiling point:571.8°C at 760 mmHg
Refractive index:1.602
Flash point:313.7°C
Vapour Pressur:1.86E-15mmHg at 25°C
Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug. It is marketed in the USA and Canada under the brand names Medrol and SoluMedrol.It is also available as a generic drug.It is a variant of prednisolone, methylated at carbon 6 of the B ring.
Specification
Items |
Specifications |
Results |
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Appearance |
White Crystalline Powder |
|
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Identification |
Infared Absorption |
Complies |
||
The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assay |
complies |
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Specific rotation |
Between -28.6°and -35.0°, measured at 20° |
-32.8° |
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Water |
not more than 0.5% |
0.12% |
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residue on ignition |
not more than 0.2% |
0.11% |
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Heavy metals |
not more than 0.001% |
complies |
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related compounds by HPLC(Test1) |
Fructose not more than 0.3% Compound A not more than 0.3% Other individual impurity not more than 0.1% Total impurities not more than 0.5% |
Fructose: 0.03% Compound A: 0.04% Total impurities: 0.07% |
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Particle size |
90% less than 350 microns |
complies |
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Limit of sulfamate and sulfate |
Sulfamate ion not more than 0.10% Sulfate ion not more than 0.10% |
complies |
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Residual Solvent |
Methylene Chloride not more than 250μg/g |
not detected |
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Acetone not mor than 2500μg/g |
||||
Isopropanol not more than 5000μg/g |
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Ethanenitrile not more than 400μg/g |
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n-hexane not more than 290μg/g |
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Ethyl Acetate not more than 2500μg/g |
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Pyridine not more than 100μg/g |
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Assay |
Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis |
99.80% |
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Conclustion |
The material complies with respect to USP32 |
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•About us
Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.
We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.
We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.
We have won ISO 9001:2000 certification. and our quality control Dept. is engaged in the activities for securing stable product quality. and it is responsible for the guidance with and the management of quality assurance activities of the entire company in order to ascertain that our manufacturing activity could be carried out in compliance with the related laws, regulations and ISO standard.
•about Noopept
Description:
Nootropic drugs are described as "Smart Drugs" because, as a whole, this drug category can have an enhancing effect in the areas of memory, focus, cognition, and neurological deficits. The bulk of these drugs have proven to improve conditions like dementia, Alzheimer's disease, and certain types of brain traumas. Noopept is one such nootropic. Noopept is a brand name for a chemical called N-phenylacetyl-L-prolylglycine ethyl ester, which is the synthetic alternative to Piracetam. In order to receive the greatest benefit the required dosage of Noopept is much lower than Piracetam. For example, 4800 mg of piracetam is equated to a daily dosage of Noopept at only 15-30 mg. After administration, Noopept appears to provide a neuro protective effect; however, researchers have yet to explain exactly why this neuro protective element occurs
Application:
it has been determined that Noopept was beneficial in restoring cognition in regard to Alzheimer's disease. It has, also, shown to prevent free radicals and pro-inflammatory cytokines accumulation, ionic imbalance, neurotrophin deficit and excitotoxicity. (Ostrovskaya, & et. al, 2014). However, as yet, the neuro protective qualities identified apparently do not affect brains that are not impaired; the uninjured daily user may experience little or no effect from Noopept (Frank, 2014). The effects of Noopept do appear to vary from user to user. Some experience a minute change in their memory and cognitive abilities, and others may experience a huge increase in memory ability and capacity to recall small details.
The short and long-term effects of Noopept use have proven to be beneficial and positive. The increased capacity of memory, attention span, and overall cognition is improved. According to experts, after tests conducted on rabbits, explain that there have been no toxic, allergic, or direct health risks associated with this nootropic.
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