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Prednisolone 50-24-8 CAS NO.50-24-8
Prednisolone Basic information |
Overview Indication Mechanism of action Pharmacokinetics Adverse reactions Precaution Overdosage Tips References |
Product Name: | Prednisolone |
Synonyms: | Budesonide Impurity 8;Prednoisolone;PREDNISOLONE GLUCOCORTICOID;PREDNISOLONE VETRANAL, 250 MG;DY-DEHYDROHYDROCORTISONE USP;DY-DEHYDROCORTISOL USP;METACORTANDRALONE USP;SCHERISOLON USP |
CAS: | 50-24-8 |
MF: | C21H28O5 |
MW: | 360.44 |
EINECS: | 200-021-7 |
Product Categories: | Steroids;Steroids & Hormones - 13C & 2H;Antitumors for Research and Experimental Use;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals;Steroid and Hormone;API;DELTA-CORTEF;Pharmaceuticals |
Mol File: | 50-24-8.mol |
Prednisolone Chemical Properties |
Melting point | 240 °C (dec.)(lit.) |
alpha | D25 +102° (dioxane) |
Boiling point | 412.46°C (rough estimate) |
density | 1.0963 (rough estimate) |
refractive index | 100 ° (C=1, Dioxane) |
Fp | 2℃ |
storage temp. | -20°C Freezer |
solubility | Very slightly soluble in water, soluble in ethanol (96 per cent) and in methanol, sparingly soluble in acetone, slightly soluble in methylene chloride. It shows polymorphism (5.9). |
form | powder |
Merck | 14,7721 |
BRN | 1354103 |
CAS DataBase Reference | 50-24-8(CAS DataBase Reference) |
EPA Substance Registry System | Pregna-1,4-diene- 3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-(50-24-8) |
Safety Information |
Hazard Codes | Xn,C,F | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Risk Statements | 22-34-11 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Safety Statements | 22-45-36/37/39-26-16 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RIDADR | UN 2811 6.1 / PGIII | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
WGK Germany | 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RTECS | TU4152000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
HS Code | 29379000 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Hazardous Substances Data | 50-24-8(Hazardous Substances Data)
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Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutritional products; Custom synthesis; Contract Manufacturing.
We pride ourelf on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.
We have some laboratories focusing on technology development and custom synthesis in Zhejiang University and Zhejiang Industry University and some Manufacturing bases which focuses on production and contract manufacturing in Zhejiang, Jiangsu and Shandong. and we have established very good cooperation and business relations with hundreds of Chinese qualified manufacturers by long-term business intercourse.
We have won ISO 9001:2000 certification. and our quality control Dept. is engaged in the activities for securing stable product quality. and it is responsible for the guidance with and the management of quality assurance activities of the entire company in order to ascertain that our manufacturing activity could be carried out in compliance with the related laws, regulations and ISO standard.
•about Noopept
Description:
Nootropic drugs are described as "Smart Drugs" because, as a whole, this drug category can have an enhancing effect in the areas of memory, focus, cognition, and neurological deficits. The bulk of these drugs have proven to improve conditions like dementia, Alzheimer's disease, and certain types of brain traumas. Noopept is one such nootropic. Noopept is a brand name for a chemical called N-phenylacetyl-L-prolylglycine ethyl ester, which is the synthetic alternative to Piracetam. In order to receive the greatest benefit the required dosage of Noopept is much lower than Piracetam. For example, 4800 mg of piracetam is equated to a daily dosage of Noopept at only 15-30 mg. After administration, Noopept appears to provide a neuro protective effect; however, researchers have yet to explain exactly why this neuro protective element occurs
Application:
it has been determined that Noopept was beneficial in restoring cognition in regard to Alzheimer's disease. It has, also, shown to prevent free radicals and pro-inflammatory cytokines accumulation, ionic imbalance, neurotrophin deficit and excitotoxicity. (Ostrovskaya, & et. al, 2014). However, as yet, the neuro protective qualities identified apparently do not affect brains that are not impaired; the uninjured daily user may experience little or no effect from Noopept (Frank, 2014). The effects of Noopept do appear to vary from user to user. Some experience a minute change in their memory and cognitive abilities, and others may experience a huge increase in memory ability and capacity to recall small details.
The short and long-term effects of Noopept use have proven to be beneficial and positive. The increased capacity of memory, attention span, and overall cognition is improved. According to experts, after tests conducted on rabbits, explain that there have been no toxic, allergic, or direct health risks associated with this nootropic.
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