Details:

Description:

Product Name:UDCA

CAS:128-13-2

MF:C24H40O4

MW:392.57

EINECS:204-879-3

Mol File: 128-13-2.mol

Product Categories:Pharmaceuticals

Use: to increase bile acid secretion, and to change the composition of bile to reduce cholesterol in bile and cholesterol

Ursodeoxycholic acid (INN, BAN and AAN), also known as ursodiol (USAN) and the abbreviation UDCA, from the root-word for bear urso, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria.

Primary bile acids are produced by the liver and stored in the gall bladder. When secreted into the intestine, primary bile acids can be metabolized into secondary bile acids by intestinal bacteria. Primary and secondary bile acids help the body digest fats. Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. Because of this property, ursodeoxycholic acid is used to treat (cholesterol) gallstones non-surgically. It is also used to relieve itching in pregnancy for some women who suffer obstetric cholestasis.

While some bile acids are known to be colon tumor promoters (e.g. deoxycholic acid), others such as ursodeoxycholic acid are thought to be chemopreventive, perhaps by inducing cellular differentiation and/or cellular senescence in colon epithelial cells.

It is believed to inhibit apoptosis.

 Medical uses:

An incomplete list of the current uses is as follows:

Reduction in gallstone formation, either in patients with gallstones unfit for cholecystectomy, or obese patients undergoing rapid weight loss to prevent gallstone formation.

For the treatment of primary biliary cholangitis (also known as primary biliary cirrhosis, PBC).

To aim to improve bile flow in patients with cystic fibrosis (controversial)

In newborn infants with impaired bile flow

After bariatric surgery, to prevent cholelithiasis due to the rapid weight loss with biliary cholesterol oversaturation and also biliary diskinesia secondary to abnormalities in cholecystokinin and biliary enervation.

 

Dosage:

1. Choleretic: Each 50mg, 150mg daily.

2. Dissolved gallstones: daily 450-600mg (8-10mg / kg), taken 2 times in the morning and evening. When gallstone removal, oral 50mg every night to prevent recurrence.

3. Hepatomegaly, chronic hepatitis: daily 8-13mg / kg, treatment for 6-24 months.

4. Bile reflux gastritis: 1000mg daily, divided into 2 times taking.

 

ITEM	SPECIFICATION	RESULTS
Appearance	Fine powder	Complies
Color	White	Complies
Odor&Taste	Characteristic	Complies
Assay	≥99%	99.13%
Heavy Metals	≤10ppm	Complies
Pb	≤2ppm	Complies
As	≤2ppm	Complies
Hg	≤1ppm	Complies
Cadmium	≤1ppm	Complies
Sulphates	≤300ppm	Complies
Ammonium	≤200ppm	Complies
Iron	≤10ppm	Complies
Microbiological Control
Total plate count	≤1000CFU/G	Complies
Yeast & mold	≤100 CFU /G	Complies
Total coli forms	≤100 CFU /G	Complies
E.coli	Negative	Negative
Salmonella	Negative	Negative

 

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests

Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.