Supply 99% Hair Loss Treatment 99% CAS 1297538-32-9 ODM-201 Powder

Details:

What's ODM-201 Powder？

Prodcut name	ODM-201
CAS No.	1297538-32-9
Appearance	white powder
Molecular Formula	C19H19ClN6O2
Molecular Weight	398.84 g/mol
Assay	99%

ODM-201 is a potent and full antagonists for human AR (hAR) with IC50 values of 26 nM by

transactivation assays in AR-HEK293 cells.IC50 value: 26 nM (in AR-HEK293 cells)

Target: androgen receptor

in vitro: ODM-201 is a new-generation androgen receptor inhibitor targeting resistance mechanisms

to androgen signaling-directed prostate cancer therapies. In competitive AR binding assays, the

inhibition constant (Ki) values of ODM-201 were 11 nM. 

in vivo: ODM-201 inhibits tumor growth in a castration-resistant VCaP xenograft model in vivo.

ODM-201 shows a significant antitumor activity with both doses, 50 mg/kg twice daily being more

efficacious compared to castrated, untreated mice (p < 0.001).
 

 

Androgenetic alopecia

       This form of hair loss is also called male pattern baldness.It can         
        be also occur in women as well

Telogen Effluvium

This form of hair loss causes the person to loose more than 90% of their hair

Alopecia Areata

This condition can affect people as young as 18.It happens when your immune systerm starts attacking

your hair follocles

Traction Alopecia

This hair loss condition can affect males or Females.It couses portions of your hair to fall out at the edges.

Hairstyles such as pigtails dreadlocks and braids are the cause of this conditon.

Anagen Effluvium

This condition causes shedding during the anagen phase or growth stage.Chemotherapy is the most

common cause.

Prostate enlargement

Dutasteride is occasionally used for treating benign prostatic hyperplasia (BPH); colloquially known as

an "enlarged prostate". It is approved by the Food and Drug Administration (FDA) in the U.S. for this

indication.

Pattern hair loss

Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea at a dosage of

0.5 mg per day.
It has been found in several studies to improve hair growth in men more rapidly and to a greater extent

than 2.5 mg/day finasteride.Dutasteride has also been used off-label in the treatment of female pattern

hair loss.

 

Prostate cancer

In those who are being regularly screened, 5α-reductase inhibitors such as finasteride and dutasteride

reduce the overall risk of being diagnosed with prostate cancer; however, there is insufficient data to

determine if they have an effect on the risk of death and may increase the chance of more serious cases

 

Excessive hair growth

Although no reports specific to dutasteride currently exist,5α-reductase inhibitors like finasteride have

been found to be effective in the treatment of hirsutism (excessive facial and/or body hair growth) in

women.In a study of 89 women with hyperandrogenism due to persistent adrenarche syndrome,

finasteride produced a 93% reduction in facial hirsutism and a 73% reduction in bodily hirsutism

after 2 years of treatment.Other studies using finasteride for hirsutism have also found it to be clearly

effective.[2] Dutasteride may be more effective than finasteride for this indication due to the fact that

its inhibition of the 5α-reductase enzyme is comparatively more complete.

 

Items	Requirements	Results
Appearance:	White Powder	White Powder
Identification
HPLC	IR spectra is consistent with CRS	Conforms
Sulphated Ash	≤0.1%	0.01%
Loss on drying	≤0.1%	0.01%
Related Matreial	Major ≤0.5% Total ≤1.0%	0.3% 0.5%
Heavy metal Pb : Cadmium(Cd) : As : Hg:	≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm	<10ppm Conforms 0.3ppm Conforms Negative
Assay	≥98%	99.2%
Conclusion:	The product conforms to BP.

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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