Veterinary Pharmaceutical CAS 16595-80-5 Levamisole Hychloride Levamisole HCl

Details:

 

Levamisole Hydrochloride 16595-80-5 
Assay: 99.6% 

Properties: white crystalline powder

Identification: positive response

Solution clarity: in line with the regulations

Ph: 3.8

Than the curl: 124.2 °

Related substances: lt;0.5%

Heavy metals: & lt;20ppm

Dry weight loss :0.08%

Burning residue :0.01%

Content: 100.3%

Levamisole Hcl is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives.IC50 value: Target: Levamisole suppresses the production of white blood cells, resulting in neutropenia and agranulocytosis. With the increasing use of levamisole as an adulterant, a number of these complications have been reported among cocaine users.

Levamisole reversibly and noncompetitively inhibits most isoforms of alkaline phosphatase (e.g., human liver, bone, kidney, and spleen) except the intestinal and placental isoform. It is thus used as an inhibitor along with substrate to reduce background alkaline phosphatase activity in biomedical assays involving detection signal amplification by intestinal alkaline phosphatase, for example in in situ hybridization or Western blot protocols. It is used to immobilize the nematode C. elegans on glass slides for imaging.

    

Application

 

1.Levamisole Hydrochloride/ Levamisole Hcl is an organic molecular entity.
2.(Levamisole Hydrochloride)is an anthelmintic. Levamisole is about twice as active as racemic and has low toxicity and side effects.
3.Levamisole Hydrochloride / L-Tetramisole as an insect repellent, it has an insect repellent and immunomodulatory activity. It is suitable for treating animal mites, hookworms, etc.
4.Levamisole can cause aphid muscle spasms and excretion with feces. Mainly used for anti-aphids and anti-hookworms.

This product is the levorotation of tetramidazole. Its activity is about 1~2 times that of tetramidazole (racemic), but its toxic and side effects are low.The drug may inhibit the microtubule structure of the worm.Levamisole also has immunomodulatory and immunomodulatory functions.It has good curative effect on roundworm, hookworm, pinworm and fecal Strongnematode disease.

Use with caution in patients with early pregnancy, abnormal liver function and decreased renal function.It is forbidden for patients with liver and kidney function, active hepatitis, early pregnancy or existing schistosomiasis.

 

How does Levamisole HCL work as an antiparasitic agent

Levamisole HCL is absorbed through the gut, can also be absorbed through the skin and is distributed throughout the body. 
Levamisole affects the neurotransmitters and paralyzes the worm (spastic paralysis). The fish then passes the inactive worms. Good gravel vacuuming is advised after treatment to remove the paralyzed (but still live) worms. 
It is not ovicidal, which means it will not affect eggs already present, but it will affect the larval stage of the worm. To ensure complete eradication of the parasite treat again after remaining eggs have hatched.
 
How does Levamisole HCL work as an immunomodulator
 
The mechanism of action for its immunostimulating effects are not well understood. It is believed that it restores cell-mediated immune function in peripheral T-lymphocytes and stimulates phagocytosis by monocytes. 
The drug appears to restore depressed immune function rather than to stimulate response to above-normal levels. There are multitudes of medical studies being done with its use in humans and animals, the goal being to attain understanding of its immunomodulating mechanism. The mechanism will be defined, with time. 
However, at the time of the writing of this article, there is no complete answer to this question. For us, it is enough to know that it does stimulate immune function in fish that are suffering due to parasites or 
disease.

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.