Gastroesophageal Reflux Disease CAS 76824-35-6 Famotidine Powder

Details:

What's CAS 76824-35-6 Famotidine

Product Name	Famotidine
Synonyms:	FAMOTIDINE;[amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s; 3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-(( diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;Famotidine USP&BP;FAMOTIDINE, IMP. A (EP) AS HYDROCHLORIDE: 3-[[[2-[DIAMINOMETHYLENE) AMINO]THIAZOL-4-YL]METHYL]-SULPHANYL]PROPANIMIDAMIDE HYDROCHLORIDE MM(CRM STANDARD);FAMOTIDINE, IMPURITY C BP STANDARD;FAMOTIDINE, IMP. B (EP) AS DIMALONATE: 3,5-[2-[[[2-[(DIAMINOMETHYLENE)AMINO]THIAZOL-4-YL] METHYL]-SULPHANYL]ETHYL]-4H-1,2,4,6-THIATRIAZINE 1,1-DIOXIDE DIMALONATE MM(CRM STANDARD)
CAS:	76824-35-6
MF:	C8H15N7O2S3
MW:	337.45
EINECS:	616-396-9
Melting point:	163-164°C
Boiling point:	562.7±60.0 °C

Famotidine (Chemical formula: C8H15N7O2S3; Brand Name: PEPCID) belongs to a histamine H2-receptor

antagonist. It appears as a white to pale yellow crystalline compound. Inside the body, its primary activity

is inhibiting the gastric secretion process, further reducing the acid concentration and volume of gastric

secretion in the stomach. Based on this property, it is used for the treatment and prevention of ulcers

occurring in the stomach and intestines. It can also treat diseases such as Zollinger-Ellison syndrome in

which the stomach accumulates excess amount of acids. Moreover, it is also applied during the treatment

of gastroesophageal reflux disease (GERD) and pathological hypersecretory conditions.

 

 

Application & Function

Famotidine is given to surgery patients before operations to prevent postoperative nausea and to reduce

the risk of aspiration pneumonitis. Famotidine is also given to some patients taking NSAIDs to prevent

peptic ulcers. It serves as an alternative to proton-pump inhibitors.It is alsogiven to dogs and cats with

acid reflux.Famotidine has also been used in combination with an H1 antagonist to treat and prevent

urticaria caused by an acute allergic reaction.

 

1.Relief of heartburn, acid indigestion, and sour stomach

2.Treatment for gastric and duodenal ulcers

3.Treatment for pathologic gastrointestinal hypersecretory conditions such as Zollinger-Ellison syndrome

and multiple endocrine adenomas

4.Treatment for gastroesophageal reflux disease (GERD)Treatment for esophagitis

5.Part of a multidrug regimen for Helicobacter pylori eradication, although omeprazole may be

somewhat more effective.

6.Prevention of NSAID-induced peptic ulcers.

7.Given to surgery patients before operations to reduce the risk of aspiration pneumonitis.

8.Famotidine is also given to dogs and cats with acid reflux.Famotidine has been used in combination

with an H1 antagonist to treat and prevent urticaria caused by an acute allergic reaction.

 

Test Item	Standard	Result
Characters
Appearance	white or yellowish-white, crystalline powder or crystals	white, crystalline powder
Identification
Infrared Absorption	The transmittance spectrum obtained by sample correspond to that by CRS	Complies
Tests
Appearance of solution	clear	Complies
Loss on Drying	NMT 0.5%	0.2%
Sulfated ash	NMT 0.1%	Complies
Heavy metals	NMT 0.001%	Complies
Related substances	Impurity A: NMT 0.15%	0.07%
	Impurity B: NMT 0.15%	0.08%
	Impurity C: NMT 0.3%	0.14%
	Impurity D: NMT 0.3%	0.16%
	Impurity F: NMT 0.15%	0.08%
	Impurity G: NMT 0.15%	0.09%
	Total impurities: NMT 1.0%	0.62%
Assay	98.5%~101.5% (Calculated on dried basis)	99.1%
Conclusion: The results conform with EP 8.0 standard

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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