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Kojic Acid 5-Hydroxy-2-(hydroxymethyl)-4-pyrone 501-30-4
Kojic acid is a kind of specialized inhibitor for melanin. It can prevent the tyrosinase activity through synthesizing with copperion in the cells after it enters skin cells. Kojic acid and its derivative has better inhibitory effect on tyrosinase than any other skin whitening agents. At present it is assigned into various kinds of cosmetics for curing freckles, spots on the skin of old man, pigmentation and acne.
Product Name: |
Kojic acid |
Synonyms: |
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one; 5-Hydroxy-2-(hydroxymethyl)-4-pyrone; 5-Hydroxy-2-hydroxymethyl-4-pyrone |
CAS RN.: |
501-30-4 |
EINECS: |
207-922-4 |
Molecular Weight: |
142.11 |
Molecular Formula: |
C6H6O4 |
Melting Point(℃): |
151-156℃ |
Water Solubility: |
SOLUBLE |
Kojic acid can also eliminate free radical, strengthen cell activity of cell and keep the food fresh. It is widely used in the fields of medicine and food.
ITEM |
STANDARD |
Apperance |
Almost White Crystalline powder |
Assay % |
>=99 |
Melting point |
152-156 ℃ |
Loss on drying % |
≤1 |
Ignition residue |
≤0.1 |
Chloride(ppm) |
≤100 |
Heavy metal(ppm) |
≤3 |
Arsenic (ppm) |
≤1 |
Ferrum (ppm) |
≤10 |
Microbiological test |
Bacteria: ≤3000CFU/gFungus: ≤100CFU/g |
Function:
1). Kojic acid can inhibit tyrosinase synthesis, so it can largely inhibit the skin melanin formation;
2). Kojic acid is able to eliminate the free radicals in the human body, strengthen the activity of the leucocyte;
3). Kojic acid have ideal effect in easing pain, relieving inflammation and curing many diseases.
Application:
* Cosmetics field
Kojic acid can inhibit the synthesis of tyrosinase, it can strongly inhibit the formation of melanin in the skin. Safe and non-toxic, and will not produce sequelae of white spots. It can effectively treat freckles, age spots, pigmentation, acne, used to add to other high-end whitening cosmetics. Kojic acid at a concentration of 20ug / ml can inhibit the activity of 70 to 80% of a variety of tyrosinase (or polyphenol oxidase PPO), and it is generally added in cosmetics at 0.5 to 2.0%.
*Food field
Kojic acid can be used as a food additive, which has the functions of preservation, antiseptic and anti-oxidation. Experiments have shown that kojic acid can inhibit the conversion of sodium nitrite in bacon to carcinogenic nitrosamines, and that the addition of kojic acid to foods will not affect the taste, aroma and texture of foods; kojic acid is also the production of maltol and ethyl maltol raw material.
*Medicine field
Since kojic acid has no mutagenic effect on eukaryotic cells, it can eliminate the free radicals in the human body and enhance the leukocyte dynamics, which is beneficial to human health. Therefore, kojic acid has been used as a raw material for cephalosporin antibiotics. Headache, toothache and local inflammation are ideal for analgesic and anti-inflammatory effects.
*Agrucultural field
Kojic acid can be used in the production of biological pesticides. Bio-fertilizer (dark red liquid) made by adding 0.5 ~ 1.0% kojic acid, whether it is sprayed at low concentration as foliar fertilizer, or produced as a growth-increasing agent for root application, this crop production promoter is effective for grain and Vegetables have obvious effects of increasing yield.
Q&A:
1.Are you a manufacturer or trade company
We have our own factory which located in Zhejiang,China.Meanwhile,we also have many parter factorier,so we can supply many kinds of relative products with very competitive price and good quality.
2.How to start an order
After negoation and communication about the price,quantity,incoterm,etc.,you give me the order contract with stamp,then I sealed it ,send back to you,also give you the proforma invoice,you can arrange the payment according the PI.
3.What’s your payment terms
If sample,small amount: T/T in advance, ,Paypal.
If commercial order ,big amount: T/T in advance,L/C at sight.
4.Can I get a free sample
If this product is not very expensive,and you demand a small sample,we can supply free sample,but not including the shipping cost,you can provide a freight collect account or arrange the shipping cost by Paypal/Westunion.
5.What's the lead time
Generally we send out your order ASAP after payment,normally
small quanitity,3-5days.
big quanitity with stock,5-7days,
if without stock,we have to calculate the production period,then give you the lead tme.
6.How do you ship the order normally
If less than 50kg,will be shipped by express,such as FEDEX,DHL.
If above 50kg,we can ship it by air or sea
For very large quantity,ship it by sea will be the best choice.
7.How do you ensure the quality of your products
Strict QC with 6 steps testing from raw material purchase to finished product.
Meanwhile,we will responsible for the goods quality after be sold.
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