Supply Antipruritic Cycloheptadine CAS 969-33-5 Cyproheptadine HCl

Details:

What's Cyproheptadine HCl

Product Name	Cyproheptadine hydrochloride
CAS	969-33-5
Synonyms	CYPROHEPTADINE HYDROCHLORIDE(GRP B SL NO.1124);Cycloheptadine Hydrochloride;1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride;4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride;4-(5h-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-piperidinhydrochloride;cyproheptadienehydrochloride;nuran;4-(5H-DIBENZO[A,D]CYCLOHEPTEN-5-YLIDINE)-METHYLPIPERIDINE HYDROCHLORIDE
MF	C21H22ClN
MW	323.86
EINECS:	213-535-1

 

Cyproheptadinehydrochloride, 4-(5H-dibenzo-[a,d]-cyclohepten-5-ylidine)-1-methylpiperidine hydrochloride

sesquihydrate(Periactin), is slightly soluble in water and sparingly solublein alcohol.
Cyproheptadine possesses both antihistamine and antiserotoninactivity and is used as an antipruritic agent.

It isindicated for the treatment of hypersensitivity reactions,perennial, and seasonal allergic rhinitis; vasomotor

rhinitis;allergic conjunctivitis, uncomplicated allergic skin manifestationsof urticaria and angioedema;

amelioration of allergicreactions to blood or plasma; and cold urticaria. It is alsoused off-label for nightmares

associated with posttraumaticstress disorder (PTSD), prevention of migraine, suppressionof vascular headaches,

and appetite stimulation. Sedation isthe most prominent side effect, and this is usually brief, disappearingafter

3 or 4 days of treatment.

Cyproheptadine hydrochloride is an antihistamine in which antiserotonin activity has been demonstrated

both in vivo and in vitro. As yet, however, there is no evidence that this action contributes to clinical

therapeutic effects. Anticholinergic and sedative effects are observed. Cyproheptadine may be more

effective than other H1 blockers in the management of cold urticaria.

 

 

Application & Function 

1. Mucocutaneous allergy: applicable to long-term, seasonal allergic rhinitis, vasomotor rhinitis, allergic

conjunctivitis, urticaria, angioneurotic edema, blood or plasma products, allergic reactions, skin scratch

disease. 

2. Motion sickness: motion sickness prevention, seasickness, halo plane. 

3. For anesthesia and surgery before and after adjuvant therapy, including sedation, hypnosis, analgesia,

antiemetic.

4. For the prevention and treatment of radiation sickness or drug-induced nausea and vomiting.finished

medicine drug pharmaceutical.

 

Test Item	Standard	Result
Characters
Appearance	white or yellowish-white, crystalline powder or crystals	white, crystalline powder
Identification
Infrared Absorption	The transmittance spectrum obtained by sample correspond to that by CRS	Complies
Tests
Appearance of solution	clear	Complies
Loss on Drying	NMT 0.5%	0.2%
Sulfated ash	NMT 0.1%	Complies
Heavy metals	NMT 0.001%	Complies
Related substances	Impurity A: NMT 0.15%	0.07%
	Impurity B: NMT 0.15%	0.08%
	Impurity C: NMT 0.3%	0.14%
	Impurity D: NMT 0.3%	0.16%
	Impurity F: NMT 0.15%	0.08%
	Impurity G: NMT 0.15%	0.09%
	Total impurities: NMT 1.0%	0.62%
Assay	98.5%~101.5% (Calculated on dried basis)	99.1%
Conclusion: The results conform with EP 8.0 standard

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

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9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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