High Quality 99% 112809-51-5 Letrozole, Clomiphene, Tamoxifen, anastrozole, Exemestane, Orlistat, Pregnenolone, TIopronin, BIcalutamide

Details:

 

1.letrozole Content: 99%

2.CAS NO: 112809-51-5

3.Molecular Formula: C17H11N5

4. Molecular Weight: 285.31

5. Appearance: white or off-white powder 

6. Melting point: 181-183 ° C

 

Letrozole is an oral non-steroidal inhibitor for the treatment of hormonally-responsive breast cancer after surgery. letrozole prevents the aromatase from producing estrogens by competitive, reversible binding to the heme of its cytochrome p450 unit, the action is specific,and letrozol does not reduce production of mineralo-or corticosteroids.

Letrozole is a new generation aromatase inhibitor, is a synthetic derivative of benzyl triazole, letrozole by inhibiting aromatase, estrogen levels drop, thereby eliminating the stimulating effect of estrogen on tumor growth. Chemotherapy and radiotherapy for breast cancer.

    

Application
 

1. Treatment of postmenopausal women with advanced breast cancer (estrogen receptor, progesterone receptor positive or unknown receptor status), used for anti-estrogen therapy after the failure of second-line treatment; 

2. For locally advanced or spread after the first-line treatment of postmenopausal breast cancer (foreign data);

3. For the received standard adjuvant ta moxifen therapy in postmenopausal breast cancer after five years of adjuvant therapy in patients with extension (foreign data);

4. Postoperative adjuvant therapy for hormone-positive early breast cancer patients.

Specification
 

Tests	Specifications	Results
Appearance	White or off-white crystaline powder	White Crystalline powder
Solubility	Soluble in Ch loroform; Soluble in ethanol when heated	Conform
ldentification	(1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm	Conform Conform
	(2)Infrared spectrum should be in accordance the dominant peak of contrast	In accordance with the dominant peak of contrast
Melting points	182°C-184°C	182°C
Related substances	≤0.5%	0.3%
Single impurity	≤0.3%	0.2%
Loss on drying	≤1.0%	0.8%
[Assay]C17H11N5 (On anhydrous basis)	≥98.0%	99.2%
Conclusion	Conforms Specifications of Enterprise Standard.

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.