Supply 99% CAS 86386-73-4 Fluconazole Powder

Details:

What's Fluconazole Powder

CAS:	86386-73-4
Product Name:	Fluconazole
MF:	C13H12F2N6O
Melting point :	138-140°C
Boiling point :	579.8±60.0 °C(Predicted)
Purity:	99%

Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic

fungal infections.Target: AntifungalFluconazole is a triazole antifungal intended for oral treatment of

superficial and systemic mycoses. In tests done in standard mycological media, the compound had minimal

inhibitory concentrations against pathogenic Candida species that were usually in excess of 100 mg/l.

 

Fluconazole inhibited branching and hyphal development in C. albicans at concentrations as low as 10(-6)

M (0.3 mg/l), but miconazole and ketoconazole were still active in these tests at concentrations 100 times

lower than this [1]. Oral fluconazole was not associated with a significantly increased risk of birth defects

overall or of 14 of the 15 specific birth defects of previous concern. Fluconazole exposure may confer an

increased risk of tetralogy of Fallot [2]. Fluconazole is predicted to be ineffective against Cryptococcus

gattii in the koala as a sole therapeutic agent administered at 10 mg/kg p.o. every 12 h [3].Clinical

indications: Balanitis; Candida infection; Cryptococcus infection; Cryptococcus neoformans meningitis;

Dermatomycosis; Female genital tract infection; Fungal infection; Fungal respiratory tract infection;

Fungal urinary tract infection; Prophylaxis; Tinea capitis; Tinea corporis; Tinea cruris; Tinea pedis .

Toxicity: Symptoms of overdose include hallucinations and paranoid behavior.

 

Application & Function

1. Fluconazole is indicated in the treatment of febrile neutropenia when fungal infections are suspected

or proven.

 

2. Fluconazole is indicated in nonimmunocompromised patients for the treatment of onychomycosis caused

by tinea unguium, Trichophyton species and Candida species.

 

3. Fluconazole is indicated for the treatment and suppression of cryptococcal meningitis.

 

4. Fluconazole is indicated in the treatment of pulmonary and disseminated coccidioidomycosis caused by

Coccidioides immitis.

 

5. Fluconazole is indicated in the treatment of vulvovaginal candidiasis caused by Candida species.

 

6. Fluconazole is indicated for the treatment of serious infections, including peritonitis, pneumonia, and

urinary tract infections, caused by susceptible Candida species.

 

7. Fluconazole is also indicated for the treatment of systemic infections caused by Candida species in

neonates.

 

8. Fluconazole is indicated for the treatment of esophageal and oropharyngeal candidiasis (thrush) caused

by Candida species.

 

9. Fluconazole is indicated for the prophylaxis of candidiasis in patients undergoing bone marrow transplant

who receive cytotoxic chemotherapy and/or radiation therapy.

Items	Standard	Results
Appearance	Off-white or white crystal or crystalline powder	White crystalline powder
Melting point	137-141ºC	140ºC
Identification	(1)   (2) should comply with standard (3) should be positive reaction	Complies Complies
Clarity of solution	Should comply with standard	Complies
Assay of fluorine	Should be between 11.1-12.4%	12.3%
Involved substance	Should comply with standard	Complies
Assay of chloride	Should comply with standard	Complies
Loss on drying	Not more than 0.5%	0.2%
Residue in ignition	Not more than 0.1%	0.02%
Heavy metals	Not more than 20ppm	Complies
Limit of microbe	Should comply with standard	Complies
Assay	C13H12F2N6O should not less than 98.5% on dry basis	10

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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