Supply 99% CAS 117704-25-3 Doramectin Powder

Details:

What's Doramectin Powder

Product name	Doramectin
CAS	117704-25-3
Assay	99%
Apprearance	White or off-white csystalline powder

 

Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment

of parasites such as gastrointestinalroundworms, lungworms, eyeworms, grubs, sucking liceand mange mites in cattle.

Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A.(manufactured

by Agrovet Market Animal Health) in an 1% Doramectin Long Acting Injectable Solution forcattle, sheep, swine and

others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days.

 

Doramectin is a new type of avermectin antiparasitic drug. Its insecticidal action is similar to that of ivermectin, both

of which can inhibit the transmission of nerve impulse between nerve muscles, causing parasites to paralyse and leave

the host and die. However, due to the high blood concentration of doramectin in Chemicalbook, the elimination is

slower (half-life of doramectin is 5.7d). The half-life of ivermectin is 4.2d), and the efficacy lasts longer, so the insecticidal

effect is better, and there is no allergic reaction, so the use of ivermectin is safer.x

 

 

Doramectin is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes),

ticks and mange (and other ectoparasites).Doramectin is a derivative of ivermectin.Its spectrum includes:Haemonchus

spp.,Ostertagia spp.,Trichostrongylusspp.,Cooperia spp., Oesophagostomum spp.,Dictyocaulus viviparus,Dermatobia

hominis,Boophilus microplus,Psoroptes bovis,among many other internal and external parasites.Doramectin is available

in 2 dosage forms: as aninjection and as a 5 mg/ml topical solution.

Doramectin is effective against the major parasitic roundworms:gastrointestinal and pulmonary. Doramectin is also

effecive against most mites and lice species,and against numerous myiases (e.g. those caused by screwworm flies,bot

flies and warble flies) usually regardless of the delivery form.

As all macrocyclic lactone doramectin acts as agonist of the GABA (gamma-aminobutyric acid) neurotransmitter in

nerve cells and also binds to glutamate-gated chloride channels in nerve and muscle cells of invertebrates. In both

cases it blocks the transmission of neuronal signals of the parasites,which are either paralyzed and expelled out of the

body,or they starve.Doramectin also affects the reproduction of some parasites by diminishing oviposition or inducing

an abnormal oogenesis.

 Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment

of parasites such as gastrointestinalroundworms,lungworms,eyeworms,grubs,sucking liceand mange mites in cattle.

Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A.(manufactured

by Agrovet Market Animal Health) in an 1% Doramectin Long Acting Injectable Solution forcattle, sheep, swine and

others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation,extending its action up to 42 days.

Items	Specification	Result
Appearance	White powder	White powder
Identification	HPLC:The retention time of major peak of test solution should correspond to that of reference solution	Conforms
	IR:Sample spectrum corresponds to that of standard spectrum	Conforms
Appearance of solution	The solution is clear and not more intensely colored than reference solution BY6	Conforms
Related Substance	Avermectin NMT 2.0%	0.008
	Total impurities NMT 5.0%	0.039
Residual Solvents	Ethanol NMT 30000ppm	360ppm
	Acetone NMT 5000ppm	140ppm
BHT	NMT 2000ppm	316ppm
Sulphated Ash	NMT 0.1%	0.0007
Heavy Metal	NMT 200ppm	<20ppm
Water	NMT 3.0%	0.018
Assay(on anhydrous and solvent free basis)	≥95%	0.981
Conclusion	meets specification

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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