Supply 99% CAS 62-31-7 Dopamine Hydrochloride

Details:

What's Dopamine hydrochloride

 

roduct Name:		Dopamine hydrochloride
Synonyms:		3-Hydroxytyramine hydrochloride
CAS No.:		62-31-7
Purity:		99%
MF:		C8H12ClNO2
Molecular Weight:		189.63900
Melting Point:		248-250 °C(lit.)
Water Solubility:		soluble
Boiling Point(ºC):		337.7ºC at 760 mmHg
Appearance:		White Powder
Application:		Pharmaceutical intermediates

Dopamine hydrochloride, a pseudoepinephrine, stimulates the -receptor and dopamine receptor directly. It has the following
effects: first, by stimulating the dopamine receptors in the kidney and mesenteric vessels, it causes the blood vessels in this
area to dilate and increase the renal blood flow. 2. It can enhance the contractile force of myocardium, but not significantly
increase the heart rate, and can be used in anti-shock therapy. 3. In large doses, the peripheral blood vessels can be contracted
to increase the total peripheral resistance and blood pressure. It is used for toxic, hemorrhagic or cardiogenic shock, especially
for patients with weakened cardiac contractility and decreased urine output, but the blood volume has been made up. Combined with
diuretics, can be used in patients with acute renal failure.

 

Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors

agonist.Target: Dopamine ReceptorDopamine (or 3,4-dihydroxyphenethylamine) is a neuroendocrine transmitter in the

catecholamine and phenethylamine families that plays a number of important roles in the brain and bodies of humans.

Several important diseases of the nervous system are associated with dysfunctions of the dopamine system. Outside

the nervous system, dopamine functions in several parts of the body as a local chemical messenger. In the blood vessels,

it inhibits norepinephrine release and acts as a vasodilator; in the kidneys, it increases sodium excretion and urine output;

in the pancreas, it reduces insulin production; in the digestive system, it reduces gastrointestinal motility and protects

intestinal mucosa; and in the immune system, it reduces the activity of lymphocytes. A variety of important drugs work

by altering the way the body makes or uses dopamine. Dopamine itself is available for intravenous injection: although

it cannot reach the brain from the bloodstream, its peripheral effects make it useful in the treatment of heart failure

or shock, especially in newborn babies. L-DOPA, the metabolic precursor of dopamine, does reach the brain and is

the most widely used treatment for Parkinson's disease. 

Test Items	Specification	Test Results
Appearance	Fine, white, crystalline, odorless powder	confirm
Identification	ABC in Pass	confirm
Solubility	Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene	confirm
USP Reference standards	USP Tetracaine Hydrochloride RS USP Endotoxin RS.	confirm
Melting point	145~150 degree	146.0~147.5 degree
Chromatographic purity	In Pass	confirm
Related substance	Not more than the reference solution 0.05%	confirm
Heavy metals	≤10ppm	confirm
PH	4.5-6.5	5.8
Residue on ignition	≤0.10%	0.05%
Loss on Drying	≤ 0.5%	0.19%
Assay	98.0 -101.0%	100.1%

 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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