Details:

Products Name: Ezetimibe

Other name: 1- (4-Fluorophenyl) -3-[3- (4-fluorophenyl) -3-hydroxy-propyl]-4- (4-hydroxyphenyl) -azetidin-2-one; ZETIA; Ezitimibe EzetimibeC24H21F2N03

CAS number: 163222-33-1

Molecular formula: C24H21F2NO3

Molecular weight: 409.43

Density: 1.334g/cm3[1]

Melting point: 164-166

Boiling point: 654.9 C at mmHg

Flash point: 349.9 ~ C

 

Ezetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.It takes effect throughacting at the brush border of the small intestine and inhibiting the absorption of cholesterol, further leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of blood cholesterol.

Item	Specifications	Results
Appearance	White to off-white powder	Complies
Identification	A. IR : Similar to Reference Substance B. Meets the requirement	Complies Complies
Specific Rotation	-25°~ -30°	-27°
Water	Not more than 0.5%	0.1%
Any single other impurity	Not more than 0.1%	0.03%
Total impurities	Not more than 1.0%	0.1%
Assay	98.5%~102.0%	99.8%
Conclusion	The results conforms with enterprise standards

 

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests

Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.