Supply Glatiramer For Multiple Sclerosis 99% CAS 28704-27-0 Glatiramer Powder

Details:

  CAS 28704-27-0 Glatiramer Powder

Prodcut name	Glatiramer acetate
Sequence	(Glu, Ala, Lys, Tyr)x•xCH3COOH
MOQ	1MG
CAS No.	147245-92-9/28704-27-0
Appearance	white powder
Molecular Formula	C25H45N5O13
Molecular Weight	623.65
Assay	98%
Application	Pharma grade or research purpose
Packing	As per your request
Storage	Preserve in tight,light-resistant containers in a cool place
Custom synthesis	Available
Supply Ability	1kg/month

 

glatiramer acetate (also known as copolymer 1, cop-1, or copaxone - as marketed by teva pharmaceuticals) is an 

immunomodulator drug currently used to treat multiple sclerosis. it is a random polymer of four amino acids found in 

myelin basic protein, namely glutamic acid, lysine, alanine, and tyrosine, and may work as a decoy for the immune system.

glatiramer acetate is approved by the food and drug administration (fda) for reducing the frequency of relapses, but not

for reducing the progression of disability. observational studies, but not randomized controlled trials, suggest that it may

reduce progression of disability.

 

although the clinical definition of multiple sclerosis requires two or more episodes of symptoms and signs, glatiramer

acetate is approved for treatment after single episodes. it is also used to treat relapsing-remitting multiple sclerosis. it is

administered by subcutaneous injection.

 

Inspection	Standard	Results
Appearances	White or Off -white powder	Conforms
Solubility	Very soluble in water and acetic	Conforms
HPLC	The principal peak in the chromatogram obtained with the test solution is similar in retention time to principal peak in the chromatogram obtained with the reference solution.	Conforms
Assay	98.0-105.0%    (anhydrous and acetic acid free subtance)	99.58%
Specific optical rotation	-66.0  to-76.0  (C=0.5; 1% acetic acid)	-72.5
Water (Karl Fischer）	≦6.0%	4.4%
pH	5.0-7.0	6.4
Amino acid  analysis	Amino acid                  limit Phe                         （1.8-2.2） Lys                          （0.9-1.3） Thr                          （0.7-1.1） Cys                            present No more than the traces of the other amino acids are present.	2.1 1.0 0.9 Present Conforms
Related Substance	Unspecified impurity for each impurity: NMT1.0%	0.29%(single largest impurity）
Acetic acid	5.0-12.0%	9.4%
MS	1019.2±1.0	1019.2
Trifluoroacetate	≦0.25%	N.D
Bacterial endotoxins	≦5IU/mg	Conforms
Residual solvent Methanol Acetonitrile Triethylamine	≦3000ppm ≦410ppm ≦320ppm ≦3000ppm	Conforms Conforms Conforms Conforms
Storage	Storage：In an air tight container,protected from light at temperature 2-8℃.

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

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9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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