Peptide Powder CAS 62568-57-4 DELTA SLEEP-INDUCING PEPTIDE DSIP Dsip Powder

Details:

What's CAS 62568-57-4 DSIP

Product name	DSIP Delta Sleep Inducing Peptide
CAS No.	62568-57-4
Molecular Formula	C35H48N10O15
Molecular Weight	848.813620 Da (g/mol)
Appearance	White Lyophilized Powder
Purity	99%min
Storage condition	2-8ºC

delta sleep-inducing peptide, abbreviated dsip, is a neuropeptide that when infused into the

mesodiencephalic ventricle of recipient rabbits induces spindle and delta eegactivity and reduced motor

activities

 

its aminoacid sequence is тrр-аlа-gly-gly-asp-ala-ser-gly-glu. however, it is the only neuropeptide in

history whose gene is unknown, raising serious questions regarding the actual existence of this peptide

in nature.

Function & Application：

many roles for dsip have been suggested following research carried out using peptide analogues

with a greater molecular stability and through measuring dsip-like immunological (dsip-li) response

by injecting dsip antiserum and antibodies.

decreases basal corticotropin level and blocks its release.

stimulates release of luteinizing hormone (lh).

stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatinsecretion.

can act as a stress limiting factor.

may have a direct or indirect effect on body temperature and alleviating hypothermia.

can normalize blood pressure and myocardial contraction.

 

it has been shown to enhance the efficiency of oxidative phosphorylation in rat mitochondria in vitro,

suggesting it may have antioxidant effects.

 

there is also conflicting evidence as to its involvement in sleep patterns. some studies suggest a link

between dsip and slow-wave sleep (sws) promotion and suppression of paradoxical sleep, while some

studies show no correlation.[28] stronger effects on sleep have been noted for the synthesized analogues

of dsip.

it may have an impact on human lens epithelial cell function via the mapk pathway, which is involved in

cell proliferation, differentiation, motility, survival, and apoptosis.

 

it has been found to have anticarcinogenic properties. in a study on mice, injecting a preparation of dsip

over the mice's lifetime decreased total spontaneous tumor incidence 2.6-fold.

the same study found it to also have geroprotective effects: it slowed down the age-related switching-off

of oestrous function; it decreased by 22.6% the frequency of chromosome aberrations inbone marrow cells

and it increased by 24.1% maximum life span in comparison with the control group.

 

levels of dsip may be significant in patients diagnosed with major depressive disorder (mdd). in several

studies, levels of dsip in the plasma and cerebrospinal fluid are significantly deviated from the norm in

patients with mdd, though there are contradictions as to whether levels are higher or lower than healthy

control patients.

 

Specifications	Results
Assay(HPLC)	98.0%~102.0%	99.4%
Appearance	White Lyophilized Powder	Complies
Identification	Positive Reaction	Complies
Melting point	224.0~227.0℃	224.0~226.0℃
Ash	≤0.1%	0.08%
Loss on drying	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.06%
Related substance	≤1.0%	0.75%
Chloride	≤50ppm	Complies
Sulphate/Barium salt	≤60ppm	Complies
Oxalate	Pass	Complies
Fe	≤5ppm	Complies
As	≤50ppm	Complies
Heavy metals	≤1ppm	Complies

 

 

 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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