Supply 99% CAS 745-65-3 Prostaglandin E1 Alprostadil Powder

Details:

What's CAS 745-65-3 Prostaglandin E1 Alprostadil Powder

Product Name	Prostaglandin E1
CAS Number	745-65-3
Synonyms	11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic acid; PGE1
Appearance	White or almost white powder
Molecular Formula	C20H34O5
Molecular Weight	354.48
Density	1.131 g/cm3
Boiling Point	529.3 °C at 760 mmHg
Flash Point	288 °C
Solubility	Insoluble in water
Assay	99%

Prostaglandin E1 is used to treat erectile dysfunction through its vasodilatation function and is sold under the American

trade name Muse or Vivus for erectile urethral embolization. It can also be used as a brand name for Caverject and

Edex, which are injectable forms. Prostaglandin E1 will be used as a penile drug delivery system to insert the urethra

for at least ten minutes before you need an erection. In contrast, the same quick effect of Caverject and Edex is also

directly injected into the penile corpus cavernosum.

 

The drug is recommended for men with erectile dysfunction. You can also use this drug to keep the patent ductus

arteriosus of the newborn. This is primarily effective when ductal ductus arteriosus is not associated with ductal

congenital heart disease, including areola lesions (ie, aortic arch disruption, aortic stenosis, dysplastic left ventricular

syndrome and aortic coarctation). The Prostaglandin E1 is used for penile erection as needed. The effect starts at about

5 to 10 minutes after administration and lasts for about 30 minutes to 1 hour.

 

PGE1 is an effective drug for opening the catheter to a catheter that relies on congenital heart disease. It can be used i

n the first week of life than the efficacy of newborns. Apnea is the main side effect, and close monitoring is essential.

Function & Application 

Prostaglandin E1 was packaged in 500 mg (0.5 mg) of 1 ml ampoule. Use one of the following methods to prepare

the infusion solution.

Dissolve an arsenic in 500 ml D5W or D10W = 1 mcg / ml (0.001 mg / ml) solution.

Given 0.05 mcg / kg / min. = 3.0 ml / kg / hr

[Body weight (kg) ÷ 10] = # mg PGE1 in 100 ml IVF, 3 ml / hr = 0.05 mcg / kg / min

A vial was diluted in 100 ml D5W or D10W = 5 mcg / ml solution. Given 0.05 mcg / kg / min. = 0.6 ml / kg / hr

Ensure that the drug is well mixed in solution and that all piping is cleared. After mixing, the solution was stabilized

for 24 hours. Prostaglandin E1 is infused through the pump through a large peripheral vein (preferably not a scalp vein)

or umbilical cord blood. There is evidence that doses greater than 0.1 mcg / kg / min are not more effective and may

lead to increased adverse events.

Response and action deadlines

Neonates usually respond with PaO2 within 10-15 minutes after the start of the drug. Some patients may react after a

few hours of drug infusion has passed. The half-life of the drug is a cycle time; therefore, continuous continuous infusion

must be maintained. Once the patient reacts, the dose can be reduced to half or less of the initial effective dose.

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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