Supply 99% CAS 363-24-6 Prostaglandin E2 PGE2 Dinoprostone Powder

Details:

What's CAS 363-24-6 Prostaglandin E2 PGE2 Powder

Product Name	Prostaglandin E2
CAS Number	363-24-6
Synonyms	DINOPROSTONE;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;(5Z,11A,13E,15S)-11,15-DIHYDROXY-9-OXO-PROSTA-5,13-DIEN-1OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIEN-1-OIC ACID;[5Z,11ALPHA,13E,15S]-11,15-DIHYDROXY-9-OXOPROSTA-5,13-DIENOIC ACID;PROSTAGLANDIN;PROSTAGLANDIN E2
Appearance	White or almost white powder
Molecular Formula	C20H32O5
Molecular Weight	352.47
EINECS	206-656-6
Solubility	Insoluble in water
Assay	99%

It is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to

release factors which stimualtes bone resorption by osteoclasts. 

As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour. It

stimulates labor and delivery by stimulating the uterine, and thus terminates pregnancy. Dinoprostone is also capable

of stimulating the smooth muscle of the gastrointestinal tract of man. 

In babies it is used in those with congenital heart defects until surgery can be carried out.

Function & Application 

Sexual dysfunction

Alprostadil is sold in the United States as urethral suppositories and in injectable form. The suppositories are sold

under the brand name MUSE. The injectable forms are Edex and Caverject. Muse delivers alprostadil as a penile

suppository, inserted into the urethra, at least ten minutes before the erection will be needed. Caverject and Edex

are similarly fast-acting, but instead are injected by syringe directly into the corpus cavernosum of the penis.

 

 

Alprostadil is also available as a generic. The major cost is that it must be mixed by a compounding pharmacy and

supplies of alprostadil may be difficult to obtain. There are different formulations, including Bimix and Trimix, which

may include papaverine and/or phentolamine. A typical mix might be 30 mg of papaverine, 2 mg of phentolamine,

and 20 mcg alprostadil. As a generic, it is much less expensive than the pre-packaged injectables. It is premixed and

must be kept refrigerated and the user must load a syringe with the quantity needed.

 

Critical limb ischemia

 Alprostadil is also used for critical limb ischemia. It increases blood flow by peripheral vasodilation within 5 minutes

and induces angiogenesis. It is most effective when the ankle pressure is at least 30 mmHg and at least one tibial

artery is patent.

Item	Test Standard		Testing Result
Appearance	Powder		Complies
Color	Orange yellow powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual acetone	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies
Conclusion: Conform with USP Standard

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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