Factory Supply Best Quality CAS 117976-90-6 Rebeprazole Sodium

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                                                                             Factory Supply Best Quality CAS 117976-90-6 Rebeprazole Sodium

Rebeprazole sodium was launched as Pariet in Japan, its first market, for the treatment of peptic ulcers including gastric and duodenal ulcers.
From 4-chloro- 2,3-dimethylpyridine N-oxide, a six step synthesis allows access to the basic skeleton after successive condensations. Rabeprazole,
a structural analog of Omeprazole, the first compound to have been marketed in this class up to now, is reported to be a more potent inhibitor
of gastric H+/K+-adenosine triphosphate (ATPase) ; a common mechanism of action of this chemical class involves the conversion at low pH to
a reactive sulphonamide that itself binds to cysteine residues located on the enzyme. Moreover, rabeprazole showed an antibacterial activity
against Helicobacter Pylori, with a MIC90 of 1.56 μg/ml.

Rebeprazole sodium has a faster onset of action compared with omeprazole, but a shorter duration of action, being extensively and rapidly
metabolized in several animal species. In clinical studies in patients with gastric ulcers, 10 and 20 mg rabeprazole sodium once-daily significantly
inhibited basal and stimulated acid output. Rabeprazole is awaiting registration in the US for treatment of gastrooesophageal reflux disease (GORD)
and other pathologic hypersecretory conditions including Zollinger-Ellison syndrome.
It belongs to national second-class drug that can be used for the treatment of gastric ulcer. It can be used for the treatment of peptic ulcer,
gastroesophageal reflux disease, zollinger-ellison syndrome and other diseases.

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development,production and sales of
animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments
ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have
won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement
win-win development.