Powder Raw Material 1953-04-4 99% Pure Galantamine Hydrobromide

Details:

Product name: Galantamine 99%

Other Names: Galanthamine Hydrobromide

CAS: 3286-46-2

EINECS No.:217-780-5

Molecular Formula: C17H21NO3.HBr;C17H22BrNO3

Molecular Weight: 368.27

Appearance: white powder to white crystal powder

Specification: 99% by HPLC

Galantamine (Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is used for the treatment of mild to moderate Alzheimer’s disease and various other memory impairments, particularly those of vascular origin.

It is an alkaloid that is obtained synthetically or from the bulbs and flowers of Galanthus Caucasicus (Caucasian snowdrop, Voronov’s snowdrop), Galanthus woronowii (Amaryllidaceae) and related genera like Narcissus (daffodil)), Leucojum(snowflake) and Lycoris including Lycoris radiata (Red Spider Lily).

Galanthamine is natural extracted from lycoris radiate,is a tertiary alkaloid derived from snow drop and closely related species. It acts as a reversible competitive acetylcholinesterase (ACHE) inhibitor, while acts weaker on butyrylcholinesterse(BuChE).it is used in the treatment of disorders of the central nerbous system and may be used as an antidote to nonpolarizing muscle relaxants.Galanthamine hydrobromide is a white to almost white powder; sparingly soluble in water; insoluble chloroform,ether and alcohol.

    

Benefit:

Due to the enhanced levels of Acetylcholine, Galantamine is responsible for a number of Nootropic benefits.

This includes better memory formation and neuroplasticity or synaptic plasticity. In other words, your brain becomes more adaptable and can respond better to new stimuli and learn with greater ease.

There is also evidence to suggest an improved speed of memory recall is also associated with this supplement. A number of users indicate that supplementation has also led to an increased attention span, improved concentration, and focus. Decision making may also be improved.

Sleep is also enhanced by this supplement. Users are able to relax more quickly and effectively. This leads not only being able to fall asleep quicker (along with lower levels of stress and anxiety) but also to sleeping deeper and waking more refreshed. This is also a popular supplement to help achieve what is known as lucid dreaming or out-of-body experiences.

Galantamine has officially been approved by the FDA for treating Alzheimer’s disease. There is additional evidence to support the contention that it might be effective in treating things like ADD/ADHD, age-related cognitive decline, and other forms of dementia.

 

Function & Application:

There are thought to be two important methods of action for Galantamine.

The first of these is by inhibiting the actions of Acetylcholinesterase.This is an enzyme that goes around the brain seeking to destroy used Acetylcholine molecules within the nerve synapses while new ones are being made for the next nerve impulse. With this enzyme having less effect, this serves to increase the amount of circulating Acetylcholine within the brain.

The second way in which this supplement is thought to work is by binding itself to Acetylcholine receptor sites. This helps to make them even more receptive to the neurotransmitter in question.

So, basically, this supplement helps to increase the level of Acetylcholine activity by working on both sides of the equation. This makes Galantamine similar to the Racetam class of supplements like piracetam, aniracetam, pramiracetam or Oxiracetam.

You can enhance the effects of this compound by using Galantamine in a nootropic stack with other Cholinergics like Alpha GPC or Citicoline.

There are also researchers who think that Galantamine is able to facilitate the release of other neurotransmitters. This would include adrenaline and noradrenaline (epinephrine and norepinephrine). This may be due to a very technical method which involves blocking potassium ion channels in your neurons.

Once the levels of these neurotransmitters are increased in the brain, this leads to a whole host of benefits related to intellectual abilities and energy. These are important effects to everyone seeking improved cognition and even an improved ability to deal with anxiety and stress.

 

Dosage:

Galantamine is a powerful brain supplement, with effects lasting as long as 6 to 12 hours, just from a fairly moderate dose. But the dosages vary quite a lot depending on the purpose for taking Galantamine and of course the user.

For most users the recommended tablet dosage is between 4 mg and 24 mg a day. Scheduling is important because lower doses throughout the day actually produce better results than one large dose.

If you’re using Galantamine to improve your cognitive abilities, your daily dose should be divided up with one dose in the morning and another dose in the early afternoon. This way you will be mentally clear all day long. If you are taking Galantamine to spur on lucid dreaming, a small dose at bedtime is good, but you will need another dose several hours later.

Specification

Item	Specifications	Results
Assay(HPLC)	98.0%~102.0%	98.9%
Appearance	off-white fine powder	Complies
Identification	IR	Complies
Melting point	156.0~160.0℃	157.0~158.0℃
Loss on drying	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.06%
Related substance	≤1.0%	0.75%
Heavy metals	≤10ppm	Complies

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.