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Fast Delivery  81409-90-7 High Purity Cabergoline 81409-90-7 on hot sale

Fast Delivery 81409-90-7 High Purity Cabergoline 81409-90-7 on hot sale

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0 Metric Ton

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  • Min.Order :0 Metric Ton
  • Purity: 99%

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Fast Delivery 81409-90-7 High Purity Cabergoline 81409-90-7 on hot sale

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  • Appearance:
  • Application:Pharmaceutical grade
  • PackAge:1kg;5kg;25kg
  • ProductionCapacity:|Metric Ton|Day
  • Storage:Cool and dry place
  • Transportation:By air;By sea,By train

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Fast Delivery  81409-90-7 High Purity Cabergoline 81409-90-7 on hot sale

Introduction :Xi'an ZB Biotech Co., Ltd is specialized in researching, producing and selling herbal extract and API powder, which are mainly used in nutraceutical, cosmetic, beverage and food additives etc.
Owing plant base, extracting and purifying in GMP workshop, concentrating on the quality and cost each link. That XAZB Biotech is aiming of benefiting the world with lowest price but best products.


We are keeping overcritical on the quality and persisting in the profession all the time. XAZB owns two standardized production workshops, advanced multifunction extractors and juice concentrate equipment, covering 12,000m2. annual dried material processed 950MT, monthly production ability 60MT. 32 scientists are in R&D team. We have strict QC standards and perfect quality guarantee system, GMP certified, also FDA, ISO9001 and Halal certified. 

 

We also build an integrative marketing center in Xi'an city, China, involving in research, test, sale and service. With full qualification and exporting experience, our products are widely sold to more than 40 countries from Europe, America, Southeast Asia, Oceania and so on


1. High quality with competitive price 81409-90-7:

We are manufacturer and we have 2 factories in China,we can provide excellent quality products with factory price.


2. Fast and safe delivery:
1) Parcels can be sent out within 3 days after payment. Tracking number is available.
2) Secure and discreet shipment. You have various choices of transportation methods.

3. We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
2) Market feedback and goods feedback are appreciated, meeting customers's requirement is our  responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

4. Exported areas:

Europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
 
5. We manufacture Herbal Extract and Active Pharmaceutical Ingredients products.

Business scope: Organic & Inorganic Chemicals , Pigments & Dye stuffs , Water treatment chemicals, Intermediates, Food & FEED additives and other.

 

 

Details:

Description

Cabergoline is a potent, selective, and long-lasting dopamine D2 receptor agonist launched in 1993 in Belgium as a prolactin inhibitor. A single 1 mg dose of cabergoline effectively prevents puerperal lactation for up to 14 days, remarkably superior to other drugs that require a daily regimen. It has a low rate of rebound breast activity and good tolerability. Cabergoline is also in clinical trials for Parkinson's disease, breast cancer, and hyperprolactinaemia.

Chemical Properties

White Crystalline Solid

Originator

Kabi Pharmacia (Sweden)

Uses

A dopamine D2-receptor agonist.

Uses

receptor stimulant

Definition

ChEBI: An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substit ted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.

Manufacturing Process

A mixture of 6-(2-propenyl)-8β-carboxy-ergoline and N-(3- dimethylaminopropyl)-N-ethyl carbodiimide in tetrahydrofuran were refluxed, with stirring and under nitrogen, for 24 h. The resultant solution was evaporated in vacuo to dryness and the residue taken up with chloroform and 5% sodium hydroxide solution. The organic phase was separated, dried over anhydrous sodium sulfate and evaporated in vacuo. The residue was chromatographed on silica (eluant chloroform with 1% methanol) to give the title compound N-(3-(dimethylamino)propyl)-N-((ethylamino)carbonyl)-8β- carboxamide-6-(2-propenyl)ergoline.

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