Powder Raw Material 2521-07-5 99% Pure 9-Methyl-9H-beta-carboline/9-ME-BC

Details:

Product name:  9-Methyl-9H-beta-carboline;
CAS No.: 2521-07-5;
Synonyms: 9H-Pyrido(3,4-b)indole, 9-methyl-;9-Methyl-9H-pyrido(3,4-b)indole;
                  9-methyl-beta-carboline
Molecular Formula:  C12H10N2;
Molecular Weight: 182.2212;
Density:  1.17g/cm3
Boiling point: 367.3°C at 760 mmHg;
Flash point: 175.9°C;
Refractive index: 1.658;
Testing Method: HPLC

Storage: Store in cool & dry place, Keep away from strong light and heat.

Shelf Life: 24Months when properly stored.

Grade: Food grade/Medicine/Injection grade

9-Me-BC or 9-Methyl-β-carboline is a novel, dopaminergic , cognitive enhancer. It has been shown to improve DA (dopamine, a neurotranmittter vital to mood, focus, vigilance and wakefulness) by inducing growth of hippocampal dopaminergic neurons. The hippocampus, by the way, is the locus of short term memory formation and storage. In addition, 9-Me-BC also has some anti-inflammatory effects. 9-Methyl-9B-Carboline is a dopaminergic enhancer. It operates primarily thorugh up-modulation, differentiation and a protective effect on dendrities and synapses all the while improving dopamine synthesis tasks.

    

Benefit:

β-Carbolines (BCs) belong to the heterogenous family of carbolines, which have been found exogenously, that is, in various fruits, meats, tobacco smoke, alcohol and coffee, but also endogenously, that is, blood, brain and CSF.
These exogenous and endogenous BCs and some of their metabolites can exert neurotoxic effects, however, an unexpected stimulatory effect of 9-methyl-β-carboline (9-me-BC) on dopaminergic neurons in primary mesencephalic cultures was recently discovered. The aim of the present study was to extend our knowledge on the stimulatory effects of 9-me-BC and to test the hypothesis that 9-me-BC may act as a  cognitiveenhancer. We found that 10 days (but not 5 days) of pharmacological treatment with 9-me-BC (i) improves spatial learning in the radial maze, (ii) elevates dopamine levels in the hippocampal formation, and (iii) results after 10 days of treatment in elongated, more complex dendritic trees and higher spine numbers on granule neurons in the dentate gyrus of 9-me-BC-treated rats.
Our results demonstrate that beyond its neuroprotective/neurorestorative and anti-inflammatory effects, 9-me-BC acts as a
cognitive enhancer in a hippocampus-dependent task, and that the behavioral effects may be associated with a stimulatory impact on hippocampal dopamine levels and dendritic and synaptic proliferation.

Specification

Item	Specifications	Results
Assay(HPLC)	98%	30%
Appearance	White fine powder	Complies
Identification	IR	Complies
Melting point	156.0~160.0℃	157.0~158.0℃
Loss on drying	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.06%
Related substance	≤1.0%	0.75%
Heavy metals	≤10ppm	Complies

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

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3. OEM/ODM Available.

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5. Sample is available for your evaluation & Formulation development.

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1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

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A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
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