Tetracycline 64-75-5
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ProName:Tetracycline hydrochloride;
CasNo:64-75-5;
Molecular Formula:C22H25ClN2O8;
Appearance:Yellow crystalline powder;
Characters Soluble in water, slightly soluble in ethanol(96%),insoluble in acetone
Identification A:TLC identification
B: about 2mg add 5ml of sulphuric acid, add the solution to 2.5ml of water
C:Reaction of chlorides
PH 1.8-2.8
Speific optical rotation -240° to -255°
Loss on drying 2.0% max
Heavy metals 50ppm max
Sulphated ash 0.5% max
Related substances 4-Epitetracycline:3.0% max
4-Epainhydrotetracycline:0.5% max
Anhydrotetrcycline: 0.5% max
2-Acetyl-2-decarbamoyltetracycline:
1.5% max
Assay 95.0-102.0%
Residual solvents Acetone: 100ppm max
N-buanol: 3000ppm max
Microbiological examiation TAMC: 1000cfu/g max
TYMC: 100cfu/g max
E.Coli: absence
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