Supply 99% CAS 58-33-3 Promethazine Hydrochloride

Details:

What's  CAS 58-33-3 Promethazine Hydrochloride Powder

Product Name	Promethazine hydrochloride
Synonyms:	10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride;PROMETHAZINE HCL;PROMETHAZINE HYDROCHLORIDE;PHENERGAN;10-(2-(dimethylamino)propyl)phenothiazinemonohydrochloride;10-(2-(dimethylamino)propyl)-phenothiazinmonohydrochloride;promethazinen-(2'-dimethylamino-2'-methylethyl)phenothiazinehydrochloride;promethiazin
CAS:	58-33-3
MF:	C17H21ClN2S
MW:	320.88
EINECS:	200-375-2

Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; sedative;

anticholinergic; antiserotoninergic; local anesthetic; in the treatment of motion sickness, cough linctuses, nausea,

and allergic conditions; used to control Parkinsonian symptoms and as central nervous system depressant; in pills,

syrup, injections and suppositories.

Application & Function

Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery,

motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you

feel sleepy/relaxed before and after surgery or to help certain narcotic pain relievers (such as meperidine) work better. It

may also be used for a short time to treat a runny nose due to the common cold.

Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes

during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural

substances (such as acetylcholine) and by acting directly on certain parts of the brain.

Promethazine Hcl(NSC-231688) is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate

mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
As a sedative,Promethazine hydrochloride.To reduce nervousness, restlessness and agitation caused by psychiatric

conditions (used for this purpose mainly in Europe)
As antiallergic medication to combat hay fever (allergic rhinitis), etc., or to treat allergic reactions, alone or in combination

with oral decongestants such as pseudoephedrine
As an adjunct treatment for anaphylactoid conditions (IM/IV route preferred)
Together with codeine or dextromethorphan against cough
As a motion sickness or seasickness remedy when used with ephedrine or pseudoephedrine
To combat moderate to severe morning sickness and hyperemesis gravidarum: In the UK, promethazine is drug of first

choice, being preferred as an older drug with which there is a greater experience of use in pregnancy (second in line

being metoclopramide or prochlorperazine).
Previously, it was used as an antipsychotic,although it is generally not administered for this purpose now; promethazine

has only approximately 1/10 of the antipsychotic strength of chlorpromazine.
Treatment for migraines; however, other similar medications, like Compazine, have been shown to have a more favorable

treatment profile,and are used almost exclusively over promethazine.

Items	Standards
Characteristics	White to the pale yellow powder
Assay(C12H12O18P2Mg3)	≥98.5%
Loss on drying	≤20%
Heavy Metals(Pb)	≤0.001%
Arsenic	≤0.0002%
PH Value(3% aqueous solution)	7.0-8.5
Color of solution	≤70
Free ascorbic acid	≤0.5%
Free phosphoric acid	≤1%
Chloride	≤0.35%
Total aerobic count	≤1000 per gram

 

 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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