Factory Supply Best Purity 99% API USP/Ep Nxl 104/Avibactam/Avibactam Sodium CAS 1192491-61-4

Details:

Product name: avibactam sodium
CAS No:1192491-61-4
Appearance: white powder
Molecular weight: 287.226
Molecular formula:C7H10N3NaO6S
Usage: Avibactam sodium is a covalent and reversible β-lactamase inhibitor, inhibits β-lactamase TEM-1 and CTX-M-15 with IC50 of 8 nM and 5 nM, respectively.
Assay: HPLC; HNRM; LC-MS
[Solubility]:Soluble in ethanol,chloroform,propylene glycol and ethylenediamine. Slightly soluble in diethyl ether. Partly soluble in water.
[Specs] NLT 99%, Food Grade, Pharmaceutical Grade
Capacity: 1000kgs per month
Source: synthetic
Place of Origin: China
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat.

    

Avibactam is a non-β-lactam β-lactamase inhibitor developed by Actavis (now Allergan) jointly with AstraZeneca. A new drug application for avibactam in combination with ceftazidime (branded as Avycaz) was approved by the FDA on February 25, 2015, for treating complicated urinary tract (cUTI) and complicated intra-abdominal infections (cIAI) caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant Gram-negative bacterial pathogens.

Benefits

The -lactamase serine nucleophilic attack avibatanamide bond, open loop to form a covalent bond, the enzyme - inhibitor complex, as an enzyme inhibition form, without hydrolysis, and then cyclization to form a lactam ring to get Avibatan Chemicalbook tan. The nucleophilic attack leads to the rate of ring-opening much higher than that of cyclization, resulting in the inhibition of-lactamase. In this process, the structure of Avibatan itself can be restored by the reverse reaction, so it has a long-term inhibitory effect.
It is one of the most promising new -lactamase inhibitors. Compared with the three listed -lactamase inhibitors, they are long-acting and covalently binding to enzyme reversibility, and do not induce -lactamase production.

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.