APIs Material Fluoxetine hcl 99% Powder Cas No.56296-78-7 Price

Details:

APIs Material Fluoxetine hcl 99% Powder Cas No.56296-78-7 Price

Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for the treatment of a variety of depressive disorders, including mild or major depressive disorder, bipolar affective disorder, psychopathic Chemicalbook depression, and depressive neuropathy. The mechanism of action is to inhibit the uptake of 5-hydroxytryptamine by neurons from the synaptic cleft and increase the availability of this neurotransmitter in the cleft, so as to improve the emotional state and treat depressive mental disorders.

Fluoxetine Hydrochloride is frequently used to treat major depression, obsessive compulsive disorder, bulimia nervosa,panic disorder, body dysmorphic disorder, premenstrual dysphoric disorder, and trichotillomania. Caution should be taken when using any SSRI for bipolar disorder as this can increase the likelihood of mania; however, fluoxetine can be used with an antipsychotic(such as quetiapine) for bipolar. It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder. Fluoxetine hcl was shown to be effective for depression in six-week-long double-blind controlled trials, where it also alleviated anxiety and improved sleep. Fluoxetine was better than placebo for the prevention of depression recurrence when the patients, who originally responded to fluoxetine, were treated for a further 38 weeks. Efficacy of fluoxetine for geriatric, as well as pediatric, depression was also demonstrated in placebo-controlled trials.

Medical uses: Fluoxetine is frequently used to treat major depressive disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder, and trichotillomania.It has also been used for cataplexy, obesity, and alcohol dependence,as well as binge eating disorder.It has also been tried as a treatment for autism spectrum disorders with moderate success in adults.

Obsessive-compulsive disorder: The efficacy of fluoxetine in the treatment of obsessive-compulsive disorder (OCD) was demonstrated in two randomized multicenter phase III clinical trials. The pooled results of these trials demonstrated that 47% of completers treated with the highest dose were "much improved" or "very much improved" after 13 weeks of treatment, compared to 11% in the placebo arm of the trial.The American Academy of Child and Adolescent Psychiatry state that SSRIs, including fluoxetine, should be used as first-line therapy in children, along with cognitive behavioral therapy (CBT), for the treatment of moderate to severe OCD.

Panic disorder: The efficacy of fluoxetine in the treatment of panic disorder was demonstrated in two 12-week randomized multicenter phase III clinical trials that enrolled patients diagnosed with panic disorder, with or without agoraphobia. In the first trial, 42% of subjects in the fluoxetine-treated arm were free of panic attacks at the end of the study, vs. 28% in the placebo arm. In the second trial, 62% of fluoxetine treated patients were free of panic attacks at the end of the study, vs. 44% in the placebo arm.

Bulimia nervosa: A 2011 systematic review of seven trials which compared fluoxetine to a placebo in the treatment of bulimia nervosa; six of which found a statistically significant reduction in symptoms such as vomiting and binge eating.However, no difference was observed between treatment arms when fluoxetine and psychotherapy were compared to psychotherapy alone.

 Q1: Can I get some samples
A: Yes, free samples(10-20g or enough to detection) are available for most of our products, you only need to pay the shipping cost.

Q2: How to confirm the quality before orders
A: Two ways, either by free samples, or send us the detailed specifications, we will arrange the production as per your requirement.

Q3: What's your MOQ
A: Normally 1 kg, but smaller quantity is also acceptable for some special products.

Q4: How about discount
A: Mainly based on quantity, also some promotional products with special discount from time to time.

Q5. What's the delivery lead time
A: 2-3 working days after payment.

Q6: How to make order & payment
A: Proforma invoice will be sent after your confirmation of the order, or You can accept payment by T/T, , Escrow, Paypal, L/C.