Supply 99% High Purity Sodium 2, 3-Dimercapto-1-Propanesulfonate CAS 4076-2-2 Dmps Powder

Details:

What's DMPS ？

Product Name	Sodium 2,3-dimercapto-1-propanesulfonate
CAS NO.:	4076/2/2
Other Names:	Sodium2,3-dimercapto-1-propanesulfonate (DMPS)
Place of Origin:	Hefei Lifeon Pharmaceutical Co.,Ltd.
Purity:	98%min
Grade :	Medicine Grade
Appearance:	White or off-white crystalline powder
Assay:	98%min
Standard	Enterprise Standard

DMPS  is a broad-spectrum antidote of heavy metals, and is also used in the therapy of hepatolenticular

degeneration, HLD (also known as Wilson's disease). DMPS effect on hydrargyrism is better than that

of dimercaptopropanol, but it has lower toxicity. DMPS is used as antidote of toxicosis from mercury,

arsenic, chromium, bismuth, copper, antimony, etc. It is also effective on hepatolenticular degeneration,

HLD (Wilson's disease) with long-term use.

 

Application & Function

DMPS is indicated for the treatment of lead poisoning in children with blood level measured above

45 µg/dL. The use of DMPS is not approved for prophylactic/prevention of lead poisoning in anticipation

of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMPS can

cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals

from parts of the body other than the central nervous system.

Another application for DMPS is for provocation of tissue heavy metals in anticipation of a urine test.

This is sometimes called a "challenge" or "provoked" heavy metals test. DMPS is used to help mobilize

heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase

the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was

shown to not reliably provide an indication of past chronic hg exposure, something it was often used

for. A 2004 study by GP Archbold, et al. called the results of a DMPS challenge test "misleading"

for the purposes of diagnosing Hg toxicity. Moreover, DMPS share the limitation of extracellular

distribution, which makes it unable to cross the cell membrane and chelate heavy metals from

intracellular sites.

The relative activities of a series of novel monoalkyl esters of 2,3-dimercapto-1-propanesulfonate

Sodium (DMPS) have been examined as agents for the mobilization of cadmium, lead and arsenic

owing to the ability of these monoesters to cross cell membranes. The monoesters were found to

be more effective than the parent compound DMPS. 

 

Item	SpecificationS	Results
Appearance	White or white-off microcrystalline powder	Conform
Heavy Metal	≤0.001%	Conform
PH	3.1 - 5.5	4.9
Sulphate ash	30.5 - 34.5%	30.6%
Loss on drying	6.5 - 8.5%	8.1%
Assay	≥98.0%	99.6%

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

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9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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