Supply 99% CAS 78415-72-2 Milrinone Powder

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What's CAS 78415-72-2 Milrinone Powder？

Product Name	Milrinone
CAS	78415-72-2
MF	C12H9N3O
MW	211.22
EINECS	278-903-6
Melting point	>300 °C
Storage temp.	2-8°C

Milrinone, commonly known and marketed under the brand name Primacor, is a medication

used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to

increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also

works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus

improving its pumping action. While it has been used in people with heart failure for many

years, studies suggest that milrinone may exhibit some negative side effects that have caused

some debate about its use clinically.

 

Overall, milrinone supports ventricular functioning of the heart by decreasing the degradation

of cAMP and thus increasing phosphorylation levels of many components in the heart that

contribute to contractility and heart rate. Milrinone use following cardiac surgery has been

under some debate because of the potential increase risk of postoperative atrial arrhythmias.

However, in the short term milrinone has been deemed beneficial to those experiencing heart

failure and an effective therapy to maintain heart function following cardiac surgeries. There is

no evidence of any long term beneficial effects on survival. In critically ill patients with evidence

of cardiac dysfunction there is limited good quality evidence to recommend its use.

 

Application & Function

Milrinone, is a medication used in patients who have heart failure. It is a phosphodiesterase 3

inhibitor that works to increase the heart's contractility and decrease pulmonary vascular

resistance. Milrinone also works to vasodilate which helps alleviate increased pressures

(afterload) on the heart, thus improving its pumping action. While it has been used in people

with heart failure for many years, recent studies suggest that milrinone may exhibit some

negative side effects that have caused some debate about its use clinically.

Overall, milrinone supports ventricular functioning of the heart by decreasing the degradation

of cAMP and thus increasing phosphorylation levels of many components in the heart that

contribute to contractility and heart rate. Milrinone use following cardiac surgery has been

under some debate because of the potential increase risk of postoperative atrial arrhythmias.

However, in the short term milrinone has been deemed beneficial to those experiencing heart

failure and an effective therapy to maintain heart function following cardiac surgeries. There is

no evidence of any long term beneficial effects on survival. 

 

Item	Test Standard		Testing Result
Appearance	Powder		Complies
Color	White Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual acetone	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies
Conclusion: Conform with USP Standard

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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