Pure 99% CAS 1197958-12-5 Ap26113 Brigatinib Ap-26113 Powder

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                                                                       Pure 99% CAS 1197958-12-5 Ap26113 Brigatinib Ap-26113 Powder

Brigatinib, also known as AP-26113, is an orally active, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK
kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts
their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. In addition, AP26113 appears to overcome
mutation-based resistance. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development; ALK
dysregulation and gene rearrangements are associated with a series of tumors. EGFR is overexpressed in a variety of cancer cell types.



Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development,production and sales of
animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments
ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have
won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement
win-win development.