Details:

Dihexa Basic Info:

Product: Dihexa

Synonyms:PNB-0408; PNB 0408; PNB0408; Dihexa; N-hexanoic-Tyr-Ile-(6) aminohexanoic amide; N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide

CAS #: 1401708-83-5
Molecular Formula: C27H44N4O5
Molecular Mass: 504.672  (g/mol)
Amino Acid Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2

Purity: 99.0%

Appearance: White Lyophilized Powder

Minimum Order Quantity: 1g

Brand Name: Yinherb

Test Method: HPLC

Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C. 

What is Dihexa

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is anoligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

According to a patent, "Short duration safety studies with Dihexa have uncovered no apparent toxicity. Of particular note is a lack of neoplastic induction, since c-Met is recognized as an oncogene. This is unsurprising sinceoncogenesis requires multiple mutations including both oncogene induction and tumor suppressor attenuation."

Dihexa Benefit:

Dihexa dramatically improves cognitive function in animal models of Alzheimer’s disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.

These statements have not been evaluated by the fda and are not intented to diagnose, treat, cure or prevent any disease.

Dihexa Dosage:

This depends on your body weight. All of the research carried out so far has used rodent studies, the rats and mice are usually injected with an effective dosage thought to be around 10 μg (mcg) per KG, in humans this is thought to be around the equivalent loading of 1.6 μg per KG in humans, so if you are: 

Dihexa Function & Application:

Dihexa is an oligopeptide drug that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met.

Item	Specifications	Results
Assay(HPLC)	98.0%~102.0%	99.4%
Appearance	White Lyophilized Powder	Complies
Identification	Positive Reaction	Complies
Melting point	224.0~227.0℃	224.0~226.0℃
Ash	≤0.1%	0.08%
Loss on drying	≤0.5%	0.11%
Residue on ignition	≤0.1%	0.06%
Related substance	≤1.0%	0.75%
Chloride	≤50ppm	Complies
Sulphate/Barium salt	≤60ppm	Complies
Oxalate	Pass	Complies
Fe	≤5ppm	Complies
As	≤50ppm	Complies
Heavy metals	≤1ppm	Complies

 

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests

Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.