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66981-73-5 for sale Good Supplier In China 66981-73-5 Tianeptine Sodium High Purity
Tianeptine Sodium High Purity 66981-73-5 for sale Good Supplier In China
Tianeputine, alias stablon. Its chemical structure belongs to the three-ring antidepressants. Its mechanism of action is a drug 5-HT reuptake agonist that acts in exactly the opposite of the selective 5-HT reuptake inhibitor.
The newly distilled 7-amino acid ethyl ethyl ester of 27.6g (0.16mo1) is dissolved in 40 ml of nitromane and, under intense stirring, adds the solution to 26.2g (26.2g) at once 0.08mo1)5,8-dichlorine-10-dioxygen-11-methyl diphenyl benzene (c, f) sulfur nitrous lychee suspended in a solution of 120 ml of nitroomethane, heated at 55 degrees C for 30min. Vacuum concentrates and the residue dissolves into water. Extracted with ether, the extract is concentrated to dry, and 36g coarse esteride is obtained. 30 kg (0.065mo1) the crude esterifier and 2.8g (0.07mo1) sodium hydroxide in 75 ml of ethanol and 25 ml of water, reflux 1h. Decompression vaporization of ethanol, the remaining liquid dissolved into 150 ml of water. The aqueous solution is extracted 2 times with 75 ml of chloroform and steamed out of water under reduced pressure. Sodium salt dissolved 150 ml of human chloroform, with aquasive sodium sulfate dry, added waterless ether to the product. Filter collection, washed with ether, 50 degrees C dry, 13g sodium nippentin, melting point 180c (decomposition).
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