Supply 98% CAS 119413-54-6 Topotecan Hcl Powder

Details:

What's CAS 119413-54-6 Topotecan Hcl Powder？

Product name	Topotecan Hcl Powder
CAS	119413-54-6
MF	C23H24ClN3O5
Appearance	White Crystalline Powder
Assay	99.5~100.5%

 

Topotecan hydrochloride is transformed by the coming of camptothecin, tolerability and toxicity characteristics are good, the main side

effect is neutropenia disease, although the latter is a dose-limiting toxicity, but no cumulative, and may be anticipate and deal with.
 

Used for small cell lung cancer and metastatic ovarian cancer after failure of primary and middle chemotherapy.

1.Topological treatment of first-line chemotherapeutic sensitive recurrent small cell lung cancer is similar or better, and good tolerance,

easy to take, low hematological toxicity;

2. Topological tiikang oral formulation as the second-line treatment of ovarian cancer has a good effect, convenient to take, low hematologic

toxicity and good tolerance;

3.Oral topotikang capsule combined with cisplatin is a safe and effective drug for the treatment of widespread small cell lung cancer.

 

1. For the treatment of essential hypertension, it can be used alone or in combination with other antihypertensive drugs (such as diuretics).

2. For the treatment of heart failure, it can be used alone or in combination with cardiotonic or diuretic Chemicalbook drugs.

3. Preventing stroke in patients with hypertension and left ventricular hypertrophy.

4. It is used to slow the progression of nephropathy in patients with type 2 diabetes associated with nephropathy and hypertension.

Analysis Test	Specification	Result
Description	white crystalline powder,odorless	Conforms
Solubility	Easily soluble in water, unsoluble in ethanol	Conforms
PH	6.0~7.5	6.9
Solution clarity and color	solution should be clear and colorless	Conforms
Related substances	5'CMP 0.3% Simple impurity Total other impurity	0.01% 0.03% 0.10%
Chloride	0.05%	Conforms
Ammonium	0.05%	Conforms
Fe	0.01%	Conforms
Phosphate	0.1%	Conforms
Loss on drying	≤6.0%	1.3%
Heavy metals	0.002%	Conforms
Arsenide	0.0001%	Conforms
Bacterial Endotoxins	0.3EU/mg	Conforms
Microbial Limit	Conforms	Conforms
Assay(on dried basis)	≥98.0%	98.8%
Conclusion: The results conform with CP2010

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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