Supply 98% CAS 123318-82-1 Clofarabine Powder

Details:

What's  CAS 123318-82-1 Clofarabine Powder？

Product name	Clofarabine Powder
CAS	123318-82-1
MF	C10H11ClFN5O3
Appearance	White Crystalline Powder
Assay	99.5~100.5%

 

Clofarabine is a purine nucleoside analogue that is a lipophilic derivative of 2-Chloro-2'-deoxyadenosine (sc-202399). The advantage to

using this compound compared to 2-Chloro-2'-deoxyadenosine is the increased stability of the acid. Studies suggest that Clofarabine

contains the best qualities of Fludarabine (sc-204755) and 2-Chloro-2'-deoxyadenosine, with increased resistance to deamination and

phosphorolysis. The compound functions by inhibiting intracellular ribonucleotide reductase and DNA polymerase, which suppresses

DNA replication. Furthermore, Clofarabine displays greater affinity towards dCK (deoxycytidine kinase, dCyd), an enzyme essential in

nucleoside phosphorylation.

 

Analysis Test	Specification	Result
Description	white crystalline powder,odorless	Conforms
Solubility	Easily soluble in water, unsoluble in ethanol	Conforms
PH	6.0~7.5	6.9
Solution clarity and color	solution should be clear and colorless	Conforms
Related substances	5'CMP 0.3% Simple impurity Total other impurity	0.01% 0.03% 0.10%
Chloride	0.05%	Conforms
Ammonium	0.05%	Conforms
Fe	0.01%	Conforms
Phosphate	0.1%	Conforms
Loss on drying	≤6.0%	1.3%
Heavy metals	0.002%	Conforms
Arsenide	0.0001%	Conforms
Bacterial Endotoxins	0.3EU/mg	Conforms
Microbial Limit	Conforms	Conforms
Assay(on dried basis)	≥98.0%	98.8%
Conclusion: The results conform with CP2010

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

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Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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