Supply 98% CAS 107007-99-8 Granisetron Hydrochloride Powder

Details:

What's CAS 107007-99-8 Granisetron Hydrochloride ？

Product name	Granisetron Hydrochloride
CAS	107007-99-8
MF	C18H25ClN4O
Appearance	White Crystalline Powder
Assay	99.5~100.5%

 

Granisetron Hydrochloride is a highly selective 5-HT3 receptor antagonist, which has good preventive and therapeutic effects on

nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Factors such as radiotherapy, chemotherapy and surgery

can induce the release of 5-HT from intestinal chromaffin cells, and 5-HT may activate the 5-HT3 receptor in the central or vagus

nerve and cause vomiting reflex. The mechanism of nausea and vomiting controlled by this product is the inhibition of nausea and

vomiting by antagonizing 5-HT3 receptors in the central chemoreceptor area and peripheral vagal terminals.Granisetron

Hydrochloride has high selectivity, no extrapyramidal reaction, excessive sedation and other side effects.

 

Items	Specifications	Results
Appearance	White or almost white powder	Conforms
Identification
A: IR Spectrum	A: Sample IR spectrum comparable with that of the standard	Conforms
B: Chloride	B: Positive	Conforms
pH	4.0~6.5	5.92
Impurity E (by TLC)	NMT0.5%	<0.5%
Loss on drying	NMT0.5%	0.03%
Heavy Metals	NMT20ppm	<20ppm
Related Compounds	Impurity A: NMT1.0%	ND
	Impurity B: NMT0.5%	ND
	Impurity C: NMT0.2%	0.04%
	Impurity D: NMT0.1%	ND
	Any other impurity : NMT1.0%	0.03%
	Total impurity: NMT1.0%	0.07%
Residual Solvents
Ethanol	NMT 1000ppm	314ppm
Isopropanol	NMT 1000ppm	13ppm
DIchloromethane	NMT 300ppm	2ppm
Assay by HPLC	97.0%~102.0%	100.10%
Conclusion	The product meets USP Specifications

 

 

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & Formulation development.

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

9. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods. 

 

Delivery & Payment Terms

Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged

in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials

and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability

of product quality from all aspects. The company has a complete sales service system, the products are exported to countries

all over the world, and have won a good international reputation with excellent quality and excellent service.

The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers,

constantly strict requirements, set goals, and implement win-win development.

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