beta-Estradiol 50-28-2 99%
β-ESTRADIOL Chemical Properties
Melting point 178-179 °C(lit.)
alpha D25 +76 to +83° (dioxane)
Boiling point 355.44°C (rough estimate)
density 1.0708 (rough estimate)
refractive index 80.4 ° (C=1, Dioxane)
Fp 2℃
storage temp. 2-8°C
solubility Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form powder
pka pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
color White to off-white
Water Solubility Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck 14,3703
BRN 1914275
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey VOXZDWNPVJITMN-ZBRFXRBCSA-N
CAS DataBase Reference 50-28-2(CAS DataBase Reference)
NIST Chemistry Reference Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry System Estradiol (50-28-2)
β-ESTRADIOL Basic information
Uses Indications and Usage Adverse reactions Contradictions
Product Name: β-ESTRADIOL
Synonyms: BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;β-Estradiol, 99% (dry wt.), ca 3% water;1,3,5-Estratriene-3,17beta-diol;17beta-Estradiol;3,17beta-Dihydroxy-1,3,5(10)-estratriene;Dihydrofolliculin;Estradiol
CAS: 50-28-2
MF: C18H24O2
MW: 272.39
EINECS: 200-023-8
Mol File: 50-28-2.mol
Safety Information
Hazard Codes T,Xn,F
Risk Statements 60-61-45-63-64-40-36-20/21/22-11-48
Safety Statements 53-22-36/37/39-45-36/37-26-16-36-20
RIDADR 2811
WGK Germany 3
RTECS KG2975000
F 8-10
HazardClass 6.1
PackingGroup III
HS Code 29372390
Hazardous Substances Data 50-28-2(Hazardous Substances Data)
Toxicity LD50 subcutaneous in rat: > 300mg/kg
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