Details:

Formal Name

(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol

CAS Number

274693-27-5

Synonyms

• AR-C 126532XX
• AZD 6140

Molecular Formula

C₂₃H₂₈F₂N₆O₄S

Formula Weight

522.6

Purity

≥95%

Formulation

A crystalline solid

Solubility

• DMF: 25 mg/ml
• DMF:PBS (pH 7.2) (1:5): 0.15 mg/ml
• DMSO: 20 mg/ml
• Ethanol: 15 mg/ml

λ_max

222, 255, 295 nm

SMILES

FC(C(F)=C1)=CC=C1[C@@H]2C[C@H]2NC3=C4C(N([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)N=N4)=NC(SCCC)=N3

InChi Code

InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 2 years

About us:

Hunan Warner Pharmaceutical Co., Ltd. is an innovation-leading pharmaceutical manufacturer. Since the company was founded in 2001, adhering to the "science and technology service health" of the enterprise purpose, adhere to the "great concentration pharmaceutical, treat people good faith" the management idea, taking the path of specialization, preliminary finished from chemical API to chemical medicine preparations, from medicinal plant, plant extraction and separation to traditional Chinese medicine preparations such as medicine, Chinese medicine two industrial chain system planning and construction of form a complete set, Research and development, production and sales in chemical medicine, traditional Chinese medicine and other fields coordinated and orderly development.

Since the establishment of the company in 2001, the company has made use of its own capital, talent, information and new drug research and development advantages, on the one hand, focusing on the research and development of new drugs, in a relatively short period of time to complete a series of new drug research and development work. With zhejiang sea is pharmaceutical co., LTD., China medicine group pharmaceutical co., LTD, hainan and brent pharmaceutical co., LTD., keep love some domestic well-known enterprises such as blessed pharmaceutical co., LTD. Signed a number of technology transfer agreement, from 2001 to now realized total technology transfer contract amount is 16.1 million yuan, become a rising star in the field of new drug technology development in hunan province. On the other hand, the company strengthens the construction of production facilities. With the approval of Hunan Provincial Drug Administration, the company has set up a modern production workshop in Liuyang Biological Medicine Park that meets the requirements of GMP. The first-phase project investment is more than 20 million yuan. A solid preparation workshop with an annual production capacity of 200 million tablets, 200 million capsules and 50 million packets of granules and an active drug production workshop with an annual production capacity of 500 tons (mainly producing active drug disodium hydrogen phosphate and sodium dihydrogen phosphate) has been built. In December 2003, all the production workshops of the company have passed the national GMP on-site inspection and obtained the GMP certificate