5-Fluorouracil 51-21-8 98%
5-Fluorouracil Chemical Properties
Melting point 282-286 °C (dec.) (lit.)
Boiling point 190-200°C/0.1mmHg
density 1.4593 (estimate)
storage temp. Store at 0-5
solubility H2O: 10 mg/mL, clear
pka pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain)
form powder
color white
PH 4.3-5.3 (10g/l, H2O, 20℃)
Water Solubility 12.2 g/L 20 ºC
Sensitive Air Sensitive
Merck 14,4181
BRN 127172
Stability: Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey GHASVSINZRGABV-UHFFFAOYSA-N
CAS DataBase Reference 51-21-8(CAS DataBase Reference)
IARC 3 (Vol. 26, Sup 7) 1987
NIST Chemistry Reference 2,4-Pyrimidinedione, 5-fluoro-(51-21-8)
EPA Substance Registry System 5-Fluorouracil (51-21-8)
5-Fluorouracil Basic information
Antimetabolite Pharmacokinetics Indications Drug interaction Adverse reactions and precautions Fluorofur Chemical property Uses Methods of production
Product Name: 5-Fluorouracil
Synonyms: [180]-5-Fluorouracil;2,4(1H,3H)-Pyrimidinedione, 5-fluoro-;2,4-dioxo-5-fluoropyrimidine;3h)-pyrimidinedione,5-fluoro-4(1h;5-faracil;5-Flouracyl;Fluoroplex;fluoro-uracile
CAS: 51-21-8
MF: C4H3FN2O2
MW: 130.08
EINECS: 200-085-6
Mol File: 51-21-8.mol
Safety Information
Hazard Codes Xn,T,C,Xi
Risk Statements 22-20/21/22-52-25
Safety Statements 36-36/37-36/37/39-22-45-26
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS YR0350000
F 10-23
Hazard Note Irritant/Highly Toxic
TSCA T
HazardClass 6.1
PackingGroup III
HS Code 29335995
Hazardous Substances Data 51-21-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 230 mg/kg
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