SAM-T 97540-22-2 ademetionine disulfate tosylate 97540-22-2 S-Adenosyl-L-methionine disulfate p-toluenesulfonate

Details:

【Item name】SAM-T;  Ademetionine disulfate tosylate
【Synonyms】SAM-T; S-Adenosyl-L-Methionone; S-Adenosyl-L-methionine Disulfate Tosylate 
【CAS NO.】97540-22-2
【Mol. Formula】C22H34N6O16S4                                        
【Mol. Weight】766.78 g/mol
【Assay】96.0%~103%
【Appearance】Off-white powder  
【Character】 hygroscopic, soluble in water
【Standard】 Medicine grade, Tech. grade
【Packing】 25kgs/drum (standard packing)
【Storage】 Tight container, protect from light

 

Ademetionine disulfate tosylate, also named S-Adenosyl-L-Methionone Disulfate Tosylate(SAM-T) is a coenzyme involved in methyl group transfers. It is a off-white powder with hygroscopic and soluble in water, It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase. Transmethylation, transsulfuration and aminopropylation are the metabolic pathways that use SAM. 
 

Quality standard 

Items		Specifications
S-Adenosyl-L-Methionine Disulfate Tosylate		96.0%~103%
SAM-e ION(Ademethionine )(HPLC)		49.5%~54.7
p-Toluenesulfonic acid (HPLC)		21.0%~ 24.0%
Sulfate (SO4) (HPLC)		23.5-26.5%
(S,S) Isomer (HPLC)		≥75%
Related substances (HPLC)	S-Adenosyl-L-Homocystsine	≤1.0%
	Adenine	≤1.0%
	Methylthioadenosine	≤1.5%
	Adenosine	≤1.0%
	Sulphated Ash	≤0.5%
	Total impurities	≤3.5%
Identification		The retention time of a majoy peak corresponds the reference sample
Water content		≤3.0%
PH (5% Aqueous solution)		1.0-2.0
Heavy metals		≤10 ppm
Lead		≤3 ppm
Cadmium		≤1 ppm
Mercury		≤0.1 ppm
Arsenic		≤2 ppm
Microbiology	Total Aerobic Cout	≤1000 CFU/g
	Yeast & Mold	≤100 CFU/g
Appearance		Off-white powder,hygroscopic,soluble in water

 

Function

S-Adenosyl-l-methionine Disulfate Tosylate (SAM-T for short) is a common cosubstrate involved in methyl group transfers. SAMe was first discovered that it can prevent liver cancer, promoting cartilaginous tissue forming and concrescence, may help fight depression, alzheimer's disease, liver disease, and the pain of osteoarthritis, is now universerally acknowleged as an important pharmaceuticals to treat liver diseases. Nowaday it is commonly used in pharmaceuticals, health care food industry both at domestic and international market.

1) S-Adenosyl-L-Methionine Disulfate Tosylate is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;

2) S-Adenosyl-L-Methionine Disulfate Tosylate has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on.

3) S-Adenosyl-L-Methionine Disulfate Tosylate has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.

4) Some research has indicated that taking SAM on a regular basis help fight depression, liver disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet proven.

 

Application
 
SAM-e have a varitety of physiological functions such as Methylation, ammonia and sulfur ,it's a kind of important physiological active substances , and play an important roles for maintaining human health. The regular dosage form:Lyophilized Powder for Injection ,Tablets,Capules,etc.
 
1) Promotes positive mood balance
SAM-e could enhance the brain's dopamine and serotonin neurotransmitters metabolism and function of information transfer.For the treatment of depression, it have a good curative effect than the commonly used drug.

2) liver health
SAM-e to virus hepatitis, cholestasis, alcoholic liver disease, including cirrhosis and other liver function disorder disorder has very good curative effect.

3) Joint Health
SAM-e in alleviating pain and improve joint function.

4) Auxiliary  treatment  for Coronary heart disease.

 

Shanghai Soyoung Biotechnology Inc. a faithful and professional supplier and exporter of healthcare raw materials for pharmacy, nutrition and food industries for years with own laboratory and GMP standard factories.

Shanghai Soyoung has R&D Center and Testing Center, and has international advanced facilities of HPLC, GC, AAS, UV, TLC, LC-MS and IR equipments. 

Shanghai Soyoung has nearly 20 years production experience, it is producing in GMP workshop, each batch pass strict testing before shipment. Strict quality control is performed in every procedure from material sourcing, processing and testing to packing.

Company name	Shanghai Soyoung Biotechnology Inc.
Main Products	Health care ingredients
Location	Shanghai,China
Business Type	Manufacturer & Trader
Year start exporting	2011
Number of employees	60-70 people
Factory area	18,000 square meters
Total annual output	180-220 tons
Main Markets	America,Europe,Mid East,Asia,South Africa and etc.
Certifications	GMP,ISO,HACCP,Kosher

 

We warmly welcome customers from at home and abroad to establish cooperation and create a bright future with us together. And leading the way to make health industries heathier, help more people healthy and happy…