Manufacturer high quality Simvastatin CAS NO.: 79902-63-9

Details:

Synonym:	(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate; Zocor
Application:	A HMGCR inhibitor and anti-proliferative agent
CAS Number:	79902-63-9
Purity:	≥99%
Molecular Weight:	418.6
Molecular Formula:	C25H38O5

    

Application

(1) The primary uses of simvastatin are for the treatment of dyslipidemia and the prevention of cardiovascular disease.
(2) It also can used for the patient with coronary heart disease.

 

Specification

TEST	STANDARD	RESULT
Characters	White to off-white powder	A white powder
Identification	IR	Conforms
	HPLC	Conforms
Specific optical rotation	+285--+298°	+290°
Solubility	Practically insoluble in water; freely soluble in chloroform, in methanol, and in alcohol; Sparingly soluble in propylene glycol; very slightly soluble in hexane	Conforms
Loss On drying	≤0.5 %	0.04%
Residue on Ignition	≤0.1%	0.04%
Heavy Metals	≤20ppm	<20ppm
Chromatographic purity
Simvastatin hydroxyacid	≤0.4%	0.09
Lovastatin and epilovastatin	≤1.0%	0.38%
Methylene simvastation	≤0.4%	0.09%
Acetyl simvastatin	≤0.4%	0.05%
Anhydro simvastatin	≤0.4%	0.10%
Simvastatin dimer	≤0.4%	0.11%
Any other individual impurity	≤0.10%	0.03%
Total impurities (except lovastatin and epilovastatin)	≤1.0%	0.52%
Residual organic solvents Methanol Ethanol Methylene chloride	≤3000ppm ≤5000ppm ≤600ppm	ND 574ppm ND
Assay (on dry basis)	98.0—102.0%	99.3%
Conclusion	It complies with all the requirements of USP34

 

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Xi'an Julong Bio-Tech Co., Ltd. is located in Xi'an City, Shaanxi Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. And advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, the products are exported to countries all over the world, and have won a good international reputation with excellent quality and excellent service.
The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, constantly strict requirements, set goals, and implement win-win development.

 

1. All inquiries will be replied within 12 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

3. OEM/ODM Available.

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development.

6. Faster delivery:Sample order in stock and 3-7 days for bulk production.

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.

8. After-Sale Service:

1) International Authorized Third-Party Test For The Products You Demand.

2) 30 Days Warranty of quality of goods.

 

 

Q: What's your MOQ
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount
A: Yes, for larger quantity, we always support with better price. 

Q: How to confirm the Product Quality before placing orders
A: You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests
Q: How to start orders or make payments
A: You can send our your Purchase order (if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.