Hydrochlorothiazide 58-93-5 99%
Hydrochlorothiazide Chemical Properties
Melting point 273 °C
Boiling point 577.0±60.0 °C(Predicted)
density 1.6761 (rough estimate)
refractive index 1.6100 (estimate)
Fp 9℃
storage temp. 2-8°C
solubility Very slightly soluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides
pka 7.9, 9.2(at 25℃)
form solid
Water Solubility 722mg/L(25 ºC)
λmax 318nm(H2O)(lit.)
Merck 14,4781
BRN 625101
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey JZUFKLXOESDKRF-UHFFFAOYSA-N
CAS DataBase Reference 58-93-5(CAS DataBase Reference)
IARC 2B (Vol. 50, 108) 2016
NIST Chemistry Reference 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide(58-93-5)
EPA Substance Registry System Hydrochlorothiazide (58-93-5)
Hydrochlorothiazide Basic information
description Chemical Properties mechanism of action Pharmacokinetics Indications Dosage Side effects Drug Interaction Uses Production method
Product Name: Hydrochlorothiazide
Synonyms: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide;2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-,1,1-dioxide;3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide;6-Chloro-3,4-dihydro-7-sulphamoyl-1,2,4-ben-zoth-iadi-azine1,1-dioxcide;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine;6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide;200-403-3
CAS: 58-93-5
MF: C7H8ClN3O4S2
MW: 297.74
EINECS: 200-403-3
Mol File: 58-93-5.mol
Safety Information
Hazard Codes Xi,T,F,Xn
Risk Statements 22-42/43-36/38-23/25-36/37/38-39/23/24/25-23/24/25-11
Safety Statements 22-24-36/37-45-33-16-7-36/37/39-27-26
RIDADR UN 1230 3/PG 2
WGK Germany 2
RTECS DK9100000
Hazard Note Irritant
TSCA Yes
HS Code 29350090
Hazardous Substances Data 58-93-5(Hazardous Substances Data)
Toxicity LD50 in mice (mg/kg): 590 i.v.; >8000 orally (Piala)
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