Cyclosporin A 59865-13-3 99%
Cyclosporin A Chemical Properties
Melting point 148-151°C
alpha D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol)
Boiling point 838.63°C (rough estimate)
density 0.9913 (rough estimate)
refractive index 1.6500 (estimate)
Fp 87℃
storage temp. 2-8°C
solubility ethanol: 30 mg/mL
pka 13.32±0.70(Predicted)
form solid
color white
Water Solubility Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck 14,2752
BRN 3647785
InChIKey PMATZTZNYRCHOR-CGLBZJNRSA-N
CAS DataBase Reference 59865-13-3(CAS DataBase Reference)
IARC 1 (Vol. 50, 100A) 2012
EPA Substance Registry System Cyclosporin A (59865-13-3)
Cyclosporin A Basic information
Immunosuppressants Pharmacological effects Pharmacokinetics Indications Drug interactions Side effects Chemical properties Production methods
Product Name: Cyclosporin A
Synonyms: ol27-400;s7481f1;sandimmun;sandimmune;Cyclospori;1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.;30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone;Cipol N
CAS: 59865-13-3
MF: C62H111N11O12
MW: 1202.61
EINECS: 611-907-1
Mol File: 59865-13-3.mol
Safety Information
Hazard Codes T,Xn,F
Risk Statements 45-60-22-40-36-20/21/22-11
Safety Statements 53-45-36/37-24/25-22-26-16
RIDADR UN 1648 3 / PGII
WGK Germany 3
RTECS GZ4120000
HS Code 29419090
Hazardous Substances Data 59865-13-3(Hazardous Substances Data)
Toxicity LD50 in mice, rats, rabbits (mg/kg): 107, 25, >10 i.v.; 2329, 1480, >1000 orally (Ryffel)
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